Zanamivir
Relenza
Revu par Sid DajaniDernière mise à jour par Michael Stewart, MRPharmSDernière mise à jour 19 janv. 2025
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Zanamivir is prescribed for influenza virus A and B infections.
You can help to prevent the flu virus from spreading to others by using clean tissues to cover your mouth and nose when you cough or sneeze, and by washing your hands regularly.
Remember to keep warm, drink plenty of fluids and stay away from crowds.
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About zanamivir
Type de médicament | Un médicament antiviral |
Utilisé pour | Treating or preventing flu (influenza). |
Aussi appelé | Relenza®, Dectova® |
Disponible sous forme de | Blisters of powder with a Diskhaler® (inhaler) and injections |
Zanamivir treats grippe (influenza) by preventing the viruses causing the infection from spreading once they are inside your body. This reduces the symptoms of the influenza infection. It also reduces the risk of other problems which can sometimes occur alongside flu, such as pneumonia. It is most effective when it is started within an hour or two of the first symptoms of infection, but it can still be effective after this time, as long as it is started within 48 hours of the first symptoms for adults, or within 36 hours for children.
Zanamivir is also used to prevent flu when there is a flu outbreak in the community, such as in epidemics and pandemics. It is used for those who have been in close contact with people with flu and for those who would be at particular risk if they developed flu (such as children, people with long-term medical conditions, and the elderly). It is most effective when treatment begins as soon as possible after the contact, but it can still be effective when started up to 36 hours afterwards.
Another antiviral medicine called oseltamivir is often prescribed in preference to zanamivir, so you will have been prescribed zanamivir because oseltamivir is not suitable for you for some reason. Zanamivir is not a substitute for seasonal flu vaccination.
Before taking zanamivir
Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking zanamivir it is important that your doctor knows:
If you are pregnant, trying for a baby or breastfeeding. Although you can take zanamivir if you are expecting or feeding a baby, it is important that your doctor knows about this so that you can be made aware of the benefits and any risks of treatment.
If you have any breathing problems (such as asthma or chronic bronchitis), or if you are using other inhalers.
If you have ever had an allergic reaction to cow's milk protein. This is different to dairy or lactose intolerance.
Si vous prenez ou utilisez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et les médecines complémentaires.
Si vous avez déjà eu une réaction allergique à un médicament.
How to take zanamivir
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about zanamivir and provide you with full instructions for using the Diskhaler® with the powder blisters.
Take zanamivir exactly as your doctor tells you to. It is a powder which is inhaled. The powder is contained in blisters in a foil disc which you load into a Diskhaler®. Your doctor or pharmacist will show you how to use the Diskhaler®.
Zanamivir is a course of treatment which usually lasts 5-10 days, although it can sometimes be prescribed for up to 28 days during an epidemic. Use the Diskhaler® for as long as your doctor has advised, even if you do not feel unwell. If you have been prescribed it because you already have flu symptoms, you will need to use two inhalations (two blisters) twice-daily for five days, preferably morning and evening. Start using it as soon as possible. If you are taking it because you have been in contact with someone with flu but you do not have any symptoms yourself, then you will need to use two inhalations (two blisters) once a day for at least ten days.
Try to use the Diskhaler® at the same times each day, as this will help you to take zanamivir regularly.
Si vous oubliez de prendre une dose, prenez-la dès que vous vous en souvenez (sauf s'il est presque l'heure de votre prochaine dose, auquel cas laissez de côté la dose oubliée). Ne prenez pas deux doses ensemble pour compenser une dose oubliée.
Tirer le meilleur parti de votre traitement
Try to help stop the spread of flu to others. You can do this by remembering to use clean tissues to cover your mouth and nose when you cough and sneeze, binning the tissues after use, and washing your hands regularly with soap and hot water.
Remember to keep warm, drink plenty of fluids and stay away from crowds. If your symptoms do not improve or they get worse, phone your doctor for further advice.
If you regularly use other inhalers and these are due at the same time as zanamivir, use your usual inhalers first and then wait a few minutes before you use zanamivir. If you use a reliever inhaler (such as salbutamol) keep this with you while you are using zanamivir, just in case you feel breathless and you need to use it.
Can zanamivir cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains the most common ones associated with zanamivir. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any continue or become troublesome.
Common zanamivir side-effects (these affect fewer than 1 in 10 people) | Que puis-je faire si je ressens cela ? |
Itchy skin rash | Si cela devient problématique, parlez-en à votre médecin |
Less common zanamivir side-effects | Que puis-je faire si je ressens cela ? |
Feeling short of breath, throat tightness, allergic-type reactions | Informez votre médecin à ce sujet |
Si vous ressentez d'autres symptômes que vous pensez être dus au médicament, parlez-en à votre médecin ou à votre pharmacien pour obtenir des conseils supplémentaires.
How to store zanamivir
Gardez tous les médicaments hors de la portée et de la vue des enfants.
Conserver dans un endroit frais et sec, à l'abri de la chaleur directe et de la lumière.
Informations importantes sur tous les médicaments
Informations importantes sur tous les médicaments
Si vous devez subir une opération ou un traitement dentaire, informez la personne qui effectue le traitement des médicaments que vous prenez.
Si vous achetez des médicaments, vérifiez avec un pharmacien qu'ils sont compatibles avec vos autres médicaments.
Ne prenez jamais plus que la dose prescrite. Si vous soupçonnez que vous ou quelqu'un d'autre avez pris une surdose de ce médicament, rendez-vous immédiatement au service des urgences de votre hôpital local. Emportez le contenant avec vous, même s'il est vide.
Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.
Ne conservez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.
Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.
Signaler les effets secondaires d'un médicament ou d'un vaccin
Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le Site web de Yellow Card.
Questions fréquemment posées
Can zanamivir be used for types of flu other than influenza?
Zanamivir is specifically an antiviral medicine used for treating or preventing flu (influenza) caused by the influenza virus. It is not indicated for other types of flu.
What should I do if I am prescribed zanamivir but I have severe asthma?
If you have breathing problems like asthma or chronic bronchitis, your doctor needs to be aware of this before you start taking zanamivir. They will consider this when prescribing the medication, and it's especially important to use your usual inhalers first and wait a few minutes before using zanamivir if they are due at the same time. Keep a reliever inhaler with you in case you feel breathless.
Does zanamivir completely cure the flu, or does it just help with symptoms?
Zanamivir works by preventing the flu viruses from spreading inside your body, which reduces the symptoms of the infection and can also lower the risk of complications such as pneumonia.
Is it safe to take zanamivir if I am allergic to dairy products like milk or cheese?
It is important for your doctor to know if you have ever had an allergic reaction to cow's milk protein. This is different from a general dairy or lactose intolerance, so ensure you specify 'cow's milk protein allergy' to your doctor.
How long after starting zanamivir should I expect to see an improvement in my flu symptoms?
Zanamivir is most effective when started early. It reduces flu symptoms by preventing the virus from spreading. Continue to use it for the full duration advised by your doctor, even if you start to feel better, as this is a course of treatment designed to be completed over 5-10 days, or sometimes longer during outbreaks.
Lectures complémentaires et références
- Manufacturer's PIL, Relenza® 5 mg/dose inhalation powder; GlaxoSmithKline UK, The electronic Medicines Compendium. Dated October 2023.
- Médicaments Complets BNF 89e Édition; Association Médicale Britannique et Société Royale Pharmaceutique de Grande-Bretagne, Londres.
À propos du critique

Sid Dajani
Sultan Dajani a obtenu son diplôme à la London School of Pharmacy en 1994 et est devenu le plus jeune membre élu du conseil de la Royal Pharmaceutical Society depuis sa fondation en 1842.
Historique de l'article
Article également disponible en Anglais, Allemand, Espagnol, Français, Italien, Portugais, Hindi, Hébreu, Arabe, and Suédois.
Prochaine révision prévue : 19 janv. 2028
19 janv. 2025 | Dernière version
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