A Study of Brenipatide in Participants With Moderate-to-Severe Alcohol Use Disorder

You might be able to join this study if you are between 18 and 75 years old and are actively looking for help to stop or reduce your drinking. It's important that you are able to attend all the study visits and follow the instructions carefully throughout the study, which includes things like keeping diaries and giving yourself injections.

However, some things would mean you can't take part. For example, if you've had problems with certain other types of substance use (other than alcohol, nicotine, or caffeine) in the last six months, or if you've had recent thoughts or actions related to harming yourself. Also, if you have severe liver disease, you wouldn't be able to join this study. The study team will check for these and other conditions to make sure the study is safe for you.

If you join this study, your involvement would last for about 56 weeks, which is just over a year. During this time, you would have regular visits to the study clinic. You would need to give yourself the study medicine (either brenipatide or the placebo) as an injection at home. You'll be shown exactly how to do this safely and how to store the medicine properly.

You'll also be asked to keep track of your progress by filling out electronic or paper diaries and completing questionnaires. These help the study team understand how you are doing. The team will provide you with all the necessary materials and support throughout your participation.