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Actif, mais pas en recrutementNAINTERVENTIONNEL

The CROCO Study: CROhn's Disease COhort Study

The CROCO Study is helping us learn more about Crohn's disease over five years. We're following people who have recently been diagnosed and are receiving the most up-to-date treatments. By regularly checking their disease, we aim to understand how it progresses and how different treatments affect it in the long run. We also want to find early signs that could tell us how severe the disease might become. This will help doctors make better treatment plans and improve the lives of people with Crohn's disease. We'll be using special scans to see changes in the gut and collecting information about their health along the way.

En un coup d'œil

Statut
Actif, mais pas en recrutement
Phase
NA
Sponsor
GLSMED Learning Health S.A.
Objectif d'inscription
533
Démarrer
01 Aug 2021
Achèvement estimé
01 Jul 2030

De quoi parle cette étude ?

The CROCO Study is all about understanding Crohn's disease better. Crohn's disease is a long-term condition that causes inflammation in the digestive system. Because it's different for everyone, doctors and researchers want to learn more about how it changes over time, especially with the newest treatments available today.

This study will follow 600 people who have recently been diagnosed with Crohn's disease over five years. By carefully observing their health, treatments, and how their disease progresses, the study hopes to find out what factors lead to clearer and more accurate predictions about how the disease will affect someone in the future. This kind of information is really important because it helps doctors choose the best treatments and manage the disease more effectively, aiming to improve the quality of life for people with Crohn's.

To do this, the study will collect lots of information, including regular check-ups, blood tests, and special scans called MREs (Magnetic Resonance Enterography) to look at the gut. All this information will help researchers understand how treatments work in the long term, track how the disease changes in the body, and ultimately develop better ways to help people living with Crohn's disease.

Points clés

  • The study aims to understand how Crohn's disease progresses over 5 years.
  • It follows people newly diagnosed with Crohn's on current treatments.
  • Participation involves regular visits, blood tests, and MRI scans.
  • The goal is to improve future treatments and predict disease severity.
  • You continue standard Crohn's care while participating.

Qui peut être éligible ?

To join the CROCO Study, you must be an adult aged 18 or over and have been diagnosed with Crohn's disease within the last 12 months. It's important that you understand what the study involves and are happy to give your written consent to take part.

There are some reasons why you might not be able to join. For example, if you are pregnant, have a serious medical condition that means you're unlikely to live for at least two more years, or if you cannot have the regular scans because of another health problem (like kidney issues) or strong claustrophobia. Also, if there's any doubt about your Crohn's diagnosis, you wouldn't be able to participate. Most importantly, you need to be willing to take part and follow the study's requirements.

Cet étude pourrait-elle vous convenir ?

Répondez à ces questions rapides pour voir si vous êtes éligible. Ceci est un guide uniquement — l'équipe de recherche prend la décision finale.

  1. Avez-vous 18 ans ou plus ?
  2. Have you been diagnosed with Crohn's disease within the last 12 months?
  3. Are you able to understand the study and agree to take part?
  4. Are you able to have MRI scans safely (e.g., no severe claustrophobia)?
  5. Are you not pregnant?
Répondez à chaque question pour voir votre résultat.

En quoi consiste la participation ?

If you join the CROCO Study, you will be followed for five years after your Crohn's diagnosis. This means you'll have regular visits where doctors will check your health, collect blood and other samples, and ask you to fill out questionnaires about how the disease affects your daily life. After the first year, you'll have visits every six months.

Crucially, you will have special scans called MREs (Magnetic Resonance Enterography) at 1, 3, and 5 years after your diagnosis. Depending on where your disease is located, you might also have other tests like colonoscopies, endoscopies, or pelvic MRI scans. You will continue to receive the standard treatments that your doctor recommends for your Crohn's disease throughout the study. Any surgeries you have during this time will also be recorded.

Risques et avantages potentiels

Taking part in this study could help doctors learn more about Crohn's disease, which might lead to better treatments for everyone in the future. While there are no direct benefits to you as an individual, you'll be closely monitored by your healthcare team. The main risks involve the extra appointments and scans, and some people find MRI scans uncomfortable or feel claustrophobic. You are completely free to leave the study at any time, for any reason, without it affecting your medical care.

Emplacements (19)

  • University Hospital CHU of Liège
    Code postal vérifié
    Liège, Belgium
  • American Gastroenterology Center
    Code postal vérifié
    Stróvolos, Cyprus
  • IBD Clinical and Research Clinic, ISCARE
    Code postal vérifié
    Prague, Tchéquie
  • Hvidovre Hospital
    Code postal vérifié
    Hvidovre, Denmark
  • Slagelse Hospital
    Code postal vérifié
    Slagelse, Denmark
  • CHU Amiens-Picardie Hôpital Sud
    Code postal vérifié
    Amiens, France
  • CHU Estaing Clermont - Ferrand
    Code postal vérifié
    Clermont-Ferrand, France
  • Claude Huriez Hospital, Lille University
    Code postal vérifié
    Lille, France
  • Azienda Ospedaliera di Padova
    Code postal vérifié
    Padova, Italy
  • Mater dei hospital
    Code postal vérifié
    Msida, Malta
  • Hospital Garcia da Orta
    Code postal vérifié
    Almada, Portugal
  • Instituto Portugues de Oncologia de Lisboa
    Code postal vérifié
    Lisbon, Portugal

Questions fréquentes

What is the main goal of the CROCO Study?

The main goal is to better understand how Crohn's disease changes over time and how different treatments affect it in the long run.

Combien de temps serai-je impliqué dans l'étude ?

You'll be followed for five years after your Crohn's disease diagnosis.

Will I still receive my regular Crohn's medication?

Yes, you will continue to receive the standard care and treatments your doctor recommends for your Crohn's disease.

Quel type de tests vais-je avoir ?

You'll have regular check-ups, blood tests, and special MRE scans at 1, 3, and 5 years. Other scans might be needed depending on your disease.

Puis-je quitter l'étude si je change d'avis ?

Yes, you can withdraw from the study at any time without it affecting your usual medical care.

Comment en savoir plus

Parlez toujours à votre médecin généraliste ou spécialiste avant de décider de participer à une étude.

Discussion

Discussion communautaire

Propulsé par notre forum à community.patient.info. Veuillez être respectueux — ceci n'est pas un avis médical.