Can I take Cannabis and Ibuprofen together?
Drug interaction guide
Originally published 25 Jan 2026
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Using cannabis and ibuprofen together may increase the risk of side effects such as stomach irritation, indigestion, or a higher risk of bleeding. It may also increase the chance of feeling dizzy, drowsy, or confused.
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Why this happens
Both substances can affect the lining of the stomach and how blood clots (pharmacodynamic effect). Additionally, cannabis may slow down the liver's ability to process certain non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen, potentially leading to higher levels of the medicine in your system (pharmacokinetic effect).
What you should do
Use caution when combining these two. If you need to take them together, use the lowest dose of ibuprofen possible for the shortest time. Watch for signs of stomach pain, dark stools, or unusual bruising. If you feel excessively dizzy or sleepy, avoid driving or operating machinery.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Clause de non-responsabilité
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historique de l'article
Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.
25 janvier 2026 | Publié à l'origine
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