Puis-je prendre l'Amlodipine et l'Atorvastatine ensemble ?

Amlodipine et atorvastatine can usually be taken together safely and it is very common for these two medicines to be prescribed together. However, taking amlodipine and atorvastatin together can increase the amount of atorvastatin in your blood.

Amlodipine can slow down the liver enzyme (CYP3A4) that is responsible for breaking down atorvastatin. Because the body processes the statin more slowly, the levels of the medicine build up in your system.

How to know if you're having a drug interaction?

You may be experiencing an interaction between amlodipine and atorvastatin if you experience:

• Muscle pain, weakness, or cramps.

• Dark-coloured pee.

• Unexplained fatigue.

• Yellowing of the skin or eyes (jaunisse).

• Stomach pain or feeling sick (nausea).

These could indicate that atorvastatin levels are higher than normal or affecting your liver or muscles.

Ce que vous devriez faire

If you notice these symptoms, you should:

• Contact your doctor immediately-don’t wait for the next appointment.

• Do not stop your medications on your own unless your doctor tells you to.

• Report all symptoms in detail, including when they started and how severe they are.

• Attend any recommended blood tests to check liver function and muscle enzymes.

This helps your doctor decide if your dose needs adjusting or if an alternative treatment is safer.

Précautions importantes

Grossesse

You must not take atorvastatin if you are pregnant or planning to become pregnant, as it can cause serious harm to an unborn baby. Use effective contraception while taking it.

Muscle pain or weakness - atorvastatine

Signalez immédiatement à votre médecin toute douleur, sensibilité ou faiblesse musculaire inexpliquée. Dans de rares cas, cela peut entraîner de graves problèmes rénaux.

Grapefruit juice consumption

Avoid drinking large amounts of grapefruit juice. It can significantly increase the levels of these medicines in your blood, making side effects much more likely.

Avertissements sur la nourriture et les boissons

Pamplemousse et jus de pamplemousse

Grapefruit can increase the amount of these medicines in your blood, which makes side effects more likely. For atorvastatin, this can increase the risk of muscle damage. For amlodipine, it can cause your blood pressure to drop too low. You should avoid drinking large amounts of grapefruit juice or eating grapefruit while taking these medicines.

Alcool

Drinking large amounts of alcohol while taking atorvastatin can increase your risk of liver problems. It is best to keep your alcohol intake within the recommended limits (no more than 14 units per week).

Utilisation d'autres médicaments

Prendre plusieurs médicaments ? Notre Vérificateur d'Interactions Médicamenteuses vous aide à vérifier si vos ordonnances, médicaments en vente libre et suppléments peuvent être pris ensemble en toute sécurité. Recherchez simplement vos médicaments pour voir les interactions potentielles et ce qu'il faut faire à leur sujet.

Avertissement

Ces informations sont fournies à des fins éducatives générales uniquement et ne doivent pas être considérées comme un substitut aux conseils médicaux professionnels. Consultez toujours votre médecin généraliste, votre pharmacien ou un autre professionnel de santé qualifié avant de prendre des décisions concernant vos médicaments. Les circonstances individuelles peuvent varier, et seul un professionnel de santé connaissant votre historique médical peut fournir des conseils personnalisés.