Puis-je prendre Apixaban et Atorvastatine ensemble ?

Pourquoi cela se produit

Apixaban and atorvastatin are processed by the same enzyme in the liver (CYP3A4). However, atorvastatin is not a strong enough inhibitor or inducer of this enzyme to change the levels of apixaban in your blood to a degree that would cause concern.

You can continue taking both medications as prescribed by your doctor. You do not need to change your routine or dose. As with any blood thinner, you should always watch for signs of unusual bleeding or bruising and report them to your healthcare provider.

Bleeding risk - apixaban

You must seek immediate medical attention if you experience a serious fall or head injury, even if you feel fine, as you are at high risk of internal bleeding. Always inform healthcare professionals, including dentists, that you are taking an anticoagulant before any procedure.

Grossesse

Do not take atorvastatine if you are pregnant or planning to become pregnant, as it can cause serious harm to an unborn baby. You must use effective contraception while taking it.

Muscle damage - atorvastatine

You must report any unexplained muscle pain, tenderness, or weakness to your doctor immediately, as this can rarely lead to serious kidney problems.

Jus de pamplemousse

Grapefruit juice can increase the level of atorvastatin in your blood, which may increase the risk of side effects like muscle pain. Avoid drinking large quantities (more than 1.2 litres per day), though a small glass is usually fine.

Alcool

While there is no direct interaction, drinking large amounts of alcohol can increase the risk of liver problems with atorvastatin and increase the risk of stomach bleeding while taking apixaban. It is best to keep to moderate limits.

Taking multiple medicines? Our Vérificateur d'Interactions Médicamenteuses helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Avertissement

Ces informations sont fournies à des fins éducatives générales uniquement et ne doivent pas être considérées comme un substitut aux conseils médicaux professionnels. Consultez toujours votre médecin généraliste, votre pharmacien ou un autre professionnel de santé qualifié avant de prendre des décisions concernant vos médicaments. Les circonstances individuelles peuvent varier, et seul un professionnel de santé connaissant votre historique médical peut fournir des conseils personnalisés.