Can I take Aspirin and Doxazosin together?
Drug interaction guide
Originally published 25 Jan 2026
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Taking aspirin and doxazosin together may slightly reduce the blood-pressure-lowering effect of doxazosin. Additionally, both medications can increase the risk of stomach irritation or bleeding, especially if taken in high doses or over a long period.
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Why this happens
Aspirin belongs to a group of medicines called NSAIDs. These can cause the body to retain salt and water and can affect certain chemicals (prostaglandins) that help keep blood vessels open. This can work against doxazosin, which is designed to relax blood vessels and lower blood pressure. Both drugs can also affect the lining of the stomach or the way blood clots.
What you should do
For most people, taking an occasional low-dose aspirin (such as 75mg for heart protection) with doxazosin is fine. However, if you are taking higher doses of aspirin for pain or inflammation, you should monitor your blood pressure regularly. If you notice your blood pressure rising, or if you experience any unusual bruising, persistent stomach pain, or black, tarry stools, contact your doctor.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Clause de non-responsabilité
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historique de l'article
Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.
25 janvier 2026 | Publié à l'origine
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