Puis-je prendre Atorvastatine et Levothyroxine ensemble ?

Pourquoi cela se produit

Atorvastatin may slightly interfere with the proteins that carry thyroid hormone in your blood, potentially increasing the amount of active levothyroxine. Additionally, if your thyroid condition is not well-controlled (hypothyroidism), it can naturally raise your cholesterol levels, making the statin appear less effective.

You can take these medicines together. However, you should have your thyroid function (TSH levels) monitored regularly by your doctor, especially when starting or changing the dose of atorvastatin. If you notice symptoms of an overactive thyroid, such as a racing heart, feeling unusually hot, or tremors, inform your GP.

Grossesse

Vous ne devez pas prendre de l'atorvastatine si vous êtes enceinte ou prévoyez de le devenir, car cela peut causer des dommages graves à un bébé à naître. Utilisez une contraception efficace pendant que vous prenez ce médicament.

Muscle disorders - atorvastatin

Consultez immédiatement un médecin si vous ressentez des douleurs musculaires inexpliquées, une sensibilité ou une faiblesse. Dans de rares cas, cela peut entraîner une affection grave appelée rhabdomyolyse, qui provoque des lésions rénales.

Heart conditions (e.g. angina, heart failure)

If you have a heart condition, your dose must be started very low and increased slowly. Contact your doctor immediately if you experience chest pain or palpitations, as levothyroxine increases the workload on your heart.

Interaction with supplements (Calcium/Iron)

Do not take calcium tablets, iron supplements, or multivitamins at the same time as levothyroxine. You must leave a gap of at least 4 hours between these supplements and your levothyroxine to ensure the medicine works.

Diabète

Levothyroxine can raise blood sugar levels. If you have diabetes, you must monitor your blood glucose more closely when starting or changing your dose, as your diabetes medication may need to be increased.

Alcool

While alcohol does not directly interact with atorvastatin, drinking large amounts of alcohol can increase the risk of liver problems and muscle side effects. It is best to keep your intake within the recommended limits (no more than 14 units per week).

It is best to avoid or strictly limit alcohol while taking levothyroxine. While there is no direct chemical reaction, alcohol can affect thyroid function and may worsen symptoms like tiredness or mood changes.

Timing of dose

Levothyroxine must be taken on an empty stomach, at least 30 to 60 minutes before breakfast or any caffeine, as food and drink significantly prevent it from being absorbed.

Jus de pamplemousse

Grapefruit juice contains compounds that can increase the level of atorvastatin in your blood. This may increase your risk of side effects, such as muscle pain or damage. Avoid drinking large quantities (more than 1.2 litres per day), though it is safest to avoid it altogether or keep intake to very small amounts.

Dairy products (Milk and Yoghurt)

Calcium found in dairy products can interfere with how your body absorbs levothyroxine, making it less effective. You should avoid eating or drinking dairy for at least 30 to 60 minutes after taking your medicine.

Caffeine (Coffee and Tea)

Caffeine can significantly reduce the absorption of levothyroxine. You should wait at least 30 to 60 minutes after taking your tablet before having a coffee or tea.

Soya products

Soya can stop your body from absorbing levothyroxine properly. If you eat a lot of soya, your doctor may need to monitor your hormone levels more closely.

Papaye

There is some evidence that eating large amounts of papaya can interfere with how levothyroxine is absorbed.

Kelp and Seaweed

These foods are naturally high in iodine. Too much iodine can interfere with your thyroid treatment and make your condition worse.

High-fibre foods

A diet very high in fibre can reduce the absorption of levothyroxine. If you significantly change your fibre intake, inform your doctor as your dose may need adjusting.

Taking multiple medicines? Our Vérificateur d'Interactions Médicamenteuses helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Avertissement

Ces informations sont fournies à des fins éducatives générales uniquement et ne doivent pas être considérées comme un substitut aux conseils médicaux professionnels. Consultez toujours votre médecin généraliste, votre pharmacien ou un autre professionnel de santé qualifié avant de prendre des décisions concernant vos médicaments. Les circonstances individuelles peuvent varier, et seul un professionnel de santé connaissant votre historique médical peut fournir des conseils personnalisés.