Can I take Candesartan cilexetil and Mirtazapine together?
Drug interaction guide
Originally published 25 Jan 2026
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Taking these two medicines together can cause your blood pressure to drop lower than intended, especially when you first start the combination or increase your dose. This might make you feel dizzy, lightheaded, or faint, particularly when standing up from a sitting or lying position.
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Why this happens
Candesartan is a blood pressure medication (an ARB), and mirtazapine (an antidepressant) can sometimes cause a side effect called orthostatic hypotension (a drop in blood pressure upon standing). When used together, these effects can add up, leading to an increased risk of low blood pressure.
What you should do
It is generally safe to take these together, but you should be cautious. Move slowly when changing positions (like getting out of bed). If you feel very dizzy or faint, sit or lie down immediately and contact your doctor. Your doctor may want to monitor your blood pressure more closely when you start mirtazapine.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Clause de non-responsabilité
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historique de l'article
Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.
25 janvier 2026 | Publié à l'origine
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