Can I take Cannabis and Paracetamol together?
Drug interaction guide
Originally published 25 Jan 2026
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There are no known significant interactions between cannabis and paracetamol. It is generally considered safe to use them together at recommended doses.
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Why this happens
Paracetamol and the main compounds in cannabis (THC and CBD) are processed by different pathways in the liver. They do not significantly interfere with how the body absorbs, breaks down, or removes each other. Additionally, they work on different systems in the body to relieve pain, so they do not typically cause dangerous additive side effects.
What you should do
You can take paracetamol while using cannabis, but always stick to the recommended dose of paracetamol (usually no more than 4g or eight 500mg tablets in 24 hours). If you are using cannabis for medicinal purposes, it is best to inform your doctor or pharmacist so they can monitor your overall pain management plan.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Clause de non-responsabilité
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historique de l'article
Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.
25 janvier 2026 | Publié à l'origine
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