Can I take Fibre supplements and Rybelsus together?
Drug interaction guide
Originally published 25 Jan 2026
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Taking fibre supplements at the same time as Rybelsus may prevent your body from absorbing the medication properly, making it less effective at controlling your blood sugar levels.
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Why this happens
Rybelsus (semaglutide) is a very sensitive tablet that must be absorbed through the stomach lining. Fibre supplements can bulk up the stomach contents and bind to the medication, physically blocking it from being absorbed into your bloodstream.
What you should do
You must take Rybelsus on an empty stomach when you first wake up with a small sip of plain water (no more than 120ml). Wait at least 30 to 60 minutes before taking your fibre supplement, eating, or taking any other oral medications.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Clause de non-responsabilité
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historique de l'article
Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.
25 janvier 2026 | Publié à l'origine

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