Can I take Losartan and Trazodone together?
Drug interaction guide
Originally published 25 Jan 2026
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Taking these two medicines together can cause your blood pressure to drop too low. This might make you feel dizzy, lightheaded, or faint, especially when you stand up quickly from a sitting or lying position.
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Why this happens
Both losartan and trazodone have the effect of lowering blood pressure. Losartan is specifically designed to do this, while trazodone (an antidepressant) can cause low blood pressure as a side effect. When used together, their effects add up.
What you should do
You should monitor your blood pressure regularly at home. Be careful when getting out of bed or standing up; move slowly to give your body time to adjust. If you feel very dizzy, sit or lie down immediately. Inform your doctor if you experience frequent dizziness or fainting, as they may need to adjust your dosages.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Clause de non-responsabilité
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historique de l'article
Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.
25 janvier 2026 | Publié à l'origine
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