Keratoconus
Dernière mise à jour 18 Aug 2020
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Keratoconus is an eye condition that affects the shape of the cornea, which is the clear outer covering of the eye. In this condition, the cornea thins and bulges outward, eventually resembling a cone shape. These corneal abnormalities, which worsen over time, can lead to nearsightedness (myopia), blurred vision that cannot be improved with corrective lenses (irregular astigmatism), and vision loss.
Description
Keratoconus is an eye condition that affects the shape of the cornea, which is the clear outer covering of the eye. In this condition, the cornea thins and bulges outward, eventually resembling a cone shape. These corneal abnormalities, which worsen over time, can lead to nearsightedness (myopia), blurred vision that cannot be improved with corrective lenses (irregular astigmatism), and vision loss.
Other corneal changes typical of keratoconus that can be seen during an eye exam include iron deposits in the cornea that form a yellow-to-brownish ring, called the Fleischer ring, surrounding the colored part of the eye (iris). Affected individuals may also develop Vogt's striae, which are thin, vertical, white lines in the tissue at the back of the cornea.
Keratoconus may affect only one eye at first, but eventually the corneas of both eyes become misshapen, although they might not be affected with the same severity. As keratoconus worsens, people with this condition can develop corneal scarring, often caused by exposure of the abnormally thin cornea to prolonged contact lens use or excessive eye rubbing.
The eye changes characteristic of keratoconus typically begin in adolescence and slowly worsen until mid-adulthood at which point the shape of the cornea remains stable.
Inheritance patterns
The source lists the following possible inheritance patterns: Autosomal recessive; Not inherited; Autosomal dominant. More than one pattern can apply in different cases.
Related genes
Other names
Bulging cornea
Conical cornea
KC
Related patient information and medicines
Patient information leaflet
Lentilles de contact
In this they are an alternative to spectacles, usually chosen for cosmet... Some conditions affecting the front of the eye (cornea) are treated using a contact lens. These include keratoconus (where the cornea is cone-shaped rather than curved), irregularities in the surface of the cornea, and anisometropia (when your two eyes have unequal ability.
Patient information leaflet
Problèmes oculaires
Conjunctivitis Conjunctivitis is inflammation or infection of the surface layer of the eye (the conj... Dry eyes and exposure kératite Syndrome de l'œil sec (also known as keratoconjunctivitis sicca, or simply dry eyes) occurs when there is a problem with the tear film that normally keeps the eye moist and lubricated. When the cornea dries out it may.
Patient information leaflet
Astigmatisme
About 1 in 5 people with Down's syndrome have this problem and have significant astigmatism. Other corneal disorders develop throughout life. The most common of these is a condition called keratoconus. This can cause significant astigmatism, as well as short sight (myopia) and corneal scarring. Complications with astigmatism Lazy eye Astigmatism.
Lectures complémentaires et références
- Keratoconus; MedlinePlus, National Library of Medicine.
- Abu-Amero KK, Al-Muammar AM, Kondkar AA. Genetics of keratoconus: where do we stand? J Ophthalmol. 2014;2014:641708. doi: 10.1155/2014/641708. Epub 2014 Aug 28.
- Bykhovskaya Y, Margines B, Rabinowitz YS. Genetics in Keratoconus: where are we? Eye Vis (Lond). 2016 Jun 27;3:16. doi: 10.1186/s40662-016-0047-5. eCollection 2016.
- Gordon-Shaag A, Millodot M, Shneor E, Liu Y. The genetic and environmental factors for keratoconus. Biomed Res Int. 2015;2015:795738. doi: 10.1155/2015/795738. Epub 2015 May 17.
- Rabinowitz YS. Keratoconus. Surv Ophthalmol. 1998 Jan-Feb;42(4):297-319. doi: 10.1016/s0039-6257(97)00119-7.
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