Can I take Alogliptin and Empagliflozin together?
Drug interaction guide
Originally published 25 Jan 2026
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Taking alogliptin and empagliflozin together can increase the risk of your blood sugar levels dropping too low (hypoglycaemia). While both drugs are designed to lower blood sugar, using them at the same time has an additive effect. You may also have a slightly higher risk of dehydration or urinary tract infections.
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Why this happens
Both medicines work in different ways to lower blood glucose: alogliptin increases insulin production after meals, while empagliflozin helps the kidneys remove sugar through urine. Because they both lower blood sugar, their combined effect is stronger than taking either one alone.
What you should do
It is common for these two medicines to be prescribed together, but you should monitor your blood sugar levels regularly as directed by your doctor. Learn to recognise the signs of low blood sugar (such as feeling shaky, sweaty, hungry, or dizzy) and always carry a quick-acting sugar source, like glucose tablets or a sugary drink. Ensure you drink plenty of water to stay hydrated.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Clause de non-responsabilité
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historique de l'article
Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.
25 janvier 2026 | Publié à l'origine
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