Can I take Atorvastatin and Paracetamol together?
Drug interaction guide
Originally published 25 Jan 2026
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There is no known harmful interaction between atorvastatin and paracetamol. It is generally considered safe to take these two medicines together at the recommended doses.
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Why this happens
Atorvastatin and paracetamol are processed by different pathways in the liver. Atorvastatin is primarily broken down by an enzyme called CYP3A4, while paracetamol is processed through different chemical pathways (glucuronidation and sulfation). Because they do not compete for the same 'machinery' in the body, they do not interfere with each other's levels.
What you should do
You can continue to take both medicines as prescribed. Always stick to the recommended dose of paracetamol (usually no more than eight 500mg tablets in 24 hours) and inform your doctor if you experience any unusual muscle pain, which is a known side effect of statins regardless of paracetamol use.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Clause de non-responsabilité
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historique de l'article
Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.
25 janvier 2026 | Publié à l'origine

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