Can I take Atorvastatin and Spironolactone together?

Why this happens

Spironolactone is a 'potassium-sparing' diuretic that prevents your body from flushing out potassium. While atorvastatin does not directly affect potassium, some studies suggest that statins may occasionally interfere with how the kidneys manage minerals, or in rare cases of muscle breakdown (rhabdomyolysis), potassium levels can rise sharply.

What you should do

It is generally safe to take these together if prescribed by your doctor, but you should have regular blood tests to check your potassium levels and kidney function. Seek medical advice if you experience unexplained muscle pain, tenderness, or weakness, or if you feel heart palpitations or unusual tiredness.

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Clause de non-responsabilité

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.