Can I take Devil's claw and Vitamin B complex together?
Drug interaction guide
Originally published 25 Jan 2026
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There are no known significant interactions between devil's claw and a standard vitamin B complex supplement. It is generally considered safe to take these two together.
Why this happens
Devil's claw and B vitamins are processed by the body through different pathways. Devil's claw is primarily used for its anti-inflammatory properties, while B vitamins act as essential nutrients for energy and cell function. They do not interfere with each other's absorption or effectiveness.
What you should do
You can take these together as directed on the packaging. However, if you have a history of stomach ulcers or gallstones, you should speak to a pharmacist or doctor before starting devil's claw, as it can increase stomach acid.
Important precautions
Stomach ulcers or gallstones
Devil's claw can increase stomach acid and stimulate bile production, which may worsen stomach ulcers, duodenal ulcers, or gallstones.
Diabetes
Devil's claw may lower blood sugar levels; you must monitor your blood glucose closely as your diabetes medication dosage may need adjustment.
Heart rhythm disorders (arrhythmias)
Devil's claw can affect heart rate and blood pressure; use with caution if you have a heart condition or take blood pressure medication.
Food and drink warnings
Alcohol
It is best to avoid or strictly limit alcohol when taking Devil's Claw. Devil's Claw can increase the production of stomach acid, and alcohol is a known stomach irritant. Combining them may increase the risk of stomach upset, irritation, or gastric ulcers. Additionally, both substances are processed by the liver; combining them may increase the strain on liver function.
It is best to avoid or strictly limit alcohol when taking Vitamin B complex. Alcohol interferes with the absorption of B vitamins (especially B1 and B12) and increases their excretion from the body, making the supplement less effective. Additionally, chronic alcohol use can lead to severe B vitamin deficiencies.
Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
Article also available in English, German, Spanish, French, Italian, Portuguese, Hindi, Hebrew, Arabic, and Swedish.
25 Jan 2026 | Originally published
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