Can I take Ezetimibe and Indapamide together?
Drug interaction guide
Originally published 25 Jan 2026
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There are no known significant interactions between ezetimibe and indapamide. It is generally considered safe to take these two medications together.
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Why this happens
Ezetimibe works in the digestive tract to reduce cholesterol absorption, while indapamide is a diuretic (water tablet) that works on the kidneys to lower blood pressure. They are processed by different pathways in the body and do not interfere with how the other is absorbed, broken down, or excreted.
What you should do
You can continue to take both medications as prescribed by your doctor. As with any medication, if you notice any new or unusual symptoms, such as extreme muscle pain or severe dizziness, you should mention this to your healthcare provider during your next check-up.
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Important precautions
Maladie du foie
You must not take this medicine if you have moderate or severe liver disease. If you develop unexplained muscle pain, tenderness, or weakness while taking it, contact your doctor immediately, as this can rarely lead to serious muscle breakdown.
Sulphonamide allergy
Do not take this medicine if you are allergic to sulphonamide antibiotics (such as sulfamethoxazole), as you may have a similar allergic reaction to indapamide.
Low potassium (Hypokalaemia)
This medicine can significantly lower your blood potassium levels. Your doctor must monitor this, especially if you have heart rhythm problems, as low potassium increases the risk of dangerous heart arrhythmias.
Food and drink warnings
Alcool
Drinking alcohol while taking indapamide can increase the blood pressure-lowering effect of the medicine. This may make you feel dizzy, lightheaded, or faint, especially when standing up quickly. It is best to keep your alcohol intake within recommended limits and see how the medicine affects you before drinking.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Clause de non-responsabilité
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historique de l'article
Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.
25 janvier 2026 | Publié à l'origine

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