Puis-je prendre la Mirtazapine et la Sertraline ensemble ?

You should only take mirtazapine et sertraline together if they have been specifically prescribed by a specialist who is monitoring you closely.

Taking them together increases your risk of syndrome sérotoninergique.

Pourquoi cela se produit

Both mirtazapine and sertraline work by increasing the levels of serotonin in the brain. When used together, their effects add up, which can lead to serotonin levels becoming dangerously high.

You may be experiencing an interaction between mirtazapine and sertraline if:

• Vous vous sentez agité, nerveux ou anormalement anxieux.

• Vous ressentez de la confusion ou des changements d'état mental.

• Vous remarquez des tremblements, des contractions musculaires ou des secousses.

• Vous avez des sueurs excessives, des rougeurs ou de la fièvre.

• Vous développez un rythme cardiaque rapide ou irrégulier.

• You experience severe drowsiness or dizziness.

• Symptoms appear soon after starting, increasing, or combining the medicines.

Si vous présentez l'un des symptômes ci-dessus, vous devriez :

• Contactez immédiatement votre médecin généraliste ou votre pharmacien pour obtenir des conseils.

• Seek urgent medical help if symptoms are severe or include high fever, confusion, or a fast heartbeat.

• Do not stop taking mirtazapine or sertraline suddenly unless advised by a healthcare professional.

• Avoid alcohol and other medicines that can affect mood or cause drowsiness unless approved.

• Informez votre professionnel de santé de tous les autres médicaments et compléments que vous prenez.

Syndrome sérotoninergique

Taking these two medicines together significantly increases the risk of serotonin syndrome, a potentially life-threatening condition. Seek immediate medical help if you experience high fever, agitation, confusion, or muscle twitching.

Suicidal thoughts and worsening of depression

These medicines can cause an increase in suicidal thoughts or self-harm, particularly in the first few weeks of treatment or when the dose is changed. Patients under 25 are at higher risk.

Agranulocytosis (low white blood cell count)

Mirtazapine can rarely cause a serious drop in white blood cells. You must contact your doctor immediately if you develop a fever, sore throat, mouth ulcers, or any other signs of infection.

Troubles de la coagulation

La sertraline peut augmenter votre risque de saignement, en particulier au niveau de l'estomac. Faites preuve de prudence si vous prenez des médicaments anticoagulants (comme la warfarine) ou des analgésiques anti-inflammatoires (comme l'ibuprofène ou l'aspirine), car cela augmente considérablement le risque de saignement grave.

Alcool

You should avoid or strictly limit alcohol while taking these medicines. Both mirtazapine and sertraline can increase the sedative effects of alcohol, making you feel more drowsy, dizzy, or uncoordinated. Mirtazapine, in particular, is very sedating.

Jus de pamplemousse

Avoid drinking large amounts of grapefruit juice. It can increase the level of sertraline in your blood, which may increase the risk of side effects. One small glass is usually fine, but it is safest to avoid it.

Caféine (café, thé, boissons énergisantes)

Mirtazapine is often taken at night because it helps with sleep. Consuming caffeine can counteract this effect and may increase feelings of restlessness or anxiety, which the medicine is intended to treat.

Taking multiple medicines? Our Vérificateur d'Interactions Médicamenteuses helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Avertissement

Ces informations sont fournies à des fins éducatives générales uniquement et ne doivent pas être considérées comme un substitut aux conseils médicaux professionnels. Consultez toujours votre médecin généraliste, votre pharmacien ou un autre professionnel de santé qualifié avant de prendre des décisions concernant vos médicaments. Les circonstances individuelles peuvent varier, et seul un professionnel de santé connaissant votre historique médical peut fournir des conseils personnalisés.