Can I take Amlopadine and Amytriptaline together?
Drug interaction guide
Originally published 24 Jan 2026
Répond aux besoins du patient lignes directrices éditoriales
- TéléchargerTélécharger
- Partager
- Langue
- Discussion
Taking amlodipine and amitriptyline together can cause your blood pressure to drop lower than intended. This may make you feel dizzy, lightheaded, or faint, especially when standing up quickly from a sitting or lying position. There is also a small risk that both medications could affect your heart rhythm.
Dans cet article :
Poursuivre la lecture ci-dessous
Why this happens
Both drugs have the effect of lowering blood pressure (amlodipine is a calcium channel blocker and amitriptyline is a tricyclic antidepressant with alpha-blocking properties). When used together, these effects add up. Additionally, both drugs can potentially interfere with the electrical signals in the heart, though this is less common.
What you should do
You can take these together, but you should be cautious. Move slowly when changing positions (like getting out of bed) to avoid dizziness. If you feel very dizzy, have a racing heartbeat, or faint, contact your doctor. Your doctor may want to monitor your blood pressure more closely when you first start this combination.
Poursuivre la lecture ci-dessous
Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Clause de non-responsabilité
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions

Traitement et médicaments
Can I take Amytriptaline and Aspirin together?
Taking amitriptyline and aspirin together can increase your risk of bleeding, particularly in the stomach or gut. You may also find that you bruise more easily.

Traitement et médicaments
Can I take Nustendi and Ramipril together?
Taking Nustendi and ramipril together can increase the risk of your kidneys not working as well as they should. It may also lead to high levels of potassium in your blood (hyperkalaemia).
Poursuivre la lecture ci-dessous
Historique de l'article
Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.
24 janvier 2026 | Publié à l'origine

Demandez, partagez, connectez-vous.
Parcourez les discussions, posez des questions et partagez vos expériences sur des centaines de sujets liés à la santé.

Vous ne vous sentez pas bien ?
Évaluez gratuitement vos symptômes en ligne
Inscrivez-vous à la newsletter destinée aux patients
Votre dose hebdomadaire de conseils santé clairs et fiables, rédigés pour vous aider à vous sentir informé, confiant et maître de la situation.
En vous abonnant, vous acceptez notre politique de confidentialité. Vous pouvez vous désabonner à tout moment. Nous ne vendons jamais vos données.