Can I take Amytriptaline and Ramipril together?
Drug interaction guide
Originally published 24 Jan 2026
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Taking amitriptyline and ramipril together can cause your blood pressure to drop lower than intended. This is most common when you first start the medication or when your dose is increased. You may feel dizzy, lightheaded, or faint, especially when standing up quickly from a sitting or lying position.
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Why this happens
Both medications have the side effect of lowering blood pressure. Ramipril is designed to do this by relaxing blood vessels, while amitriptyline can interfere with the body's natural reflexes that maintain blood pressure when you change position. When used together, these effects add up.
What you should do
It is usually safe to take these together, but you should be cautious. To prevent dizziness, try to get up slowly from a bed or chair. If you feel very dizzy, sit or lie down immediately. Monitor your blood pressure at home if possible and tell your doctor if you feel constantly lightheaded or if you have a fainting spell.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Clause de non-responsabilité
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historique de l'article
Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.
24 janvier 2026 | Publié à l'origine
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