Can I take Lions mane and Shiitake together?
Drug interaction guide
Originally published 24 Jan 2026
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There are no known harmful interactions between Lion's Mane (Hericium erinaceus) and Shiitake (Lentinula edodes) mushrooms. Both are commonly consumed together as food or supplements.
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Why this happens
Both mushrooms contain bioactive compounds like beta-glucans that support the immune system. They do not interfere with each other's absorption or breakdown in the body. Instead, they may have a complementary effect on general health.
What you should do
It is generally safe to take these together. However, if you are taking blood-thinning medication (like warfarin) or diabetes medication, speak to your doctor first, as both mushrooms may have mild effects on blood clotting and blood sugar levels.
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Using other medicines?
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Clause de non-responsabilité
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historique de l'article
Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.
24 janvier 2026 | Publié à l'origine
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