Puis-je prendre Amitriptyline et Tizanidine ensemble ?

Pourquoi cela se produit

Both drugs have a 'depressing' effect on the central nervous system (brain and nerves). When used together, these effects are added together (additive effect). Additionally, both medications can lower blood pressure and slow down your heart rate.

You should speak to your doctor before taking these two medicines together. If your doctor prescribes both, they may start you on a lower dose and monitor you closely. Do not drive or operate machinery until you know how this combination affects you. Seek medical help immediately if you feel very faint, confused, or have a very slow heartbeat.

Idées suicidaires et changements d'humeur

L'amitriptyline peut augmenter le risque de pensées suicidaires ou d'automutilation, en particulier lors du début du traitement ou du changement de doses. Consultez immédiatement un médecin si votre humeur change ou si vous vous sentez déprimé.

Drowsiness and coordination

Both medicines cause significant drowsiness and slow your reactions. Taking them together greatly increases this effect, making it dangerous to drive, use tools, or operate machinery until you know how they affect you.

Liver or kidney problems

You must not take tizanidine if you have severe liver problems. If you have kidney issues, your doctor must start you on a very low dose, as the medicine can build up to dangerous levels in your body.

Conditions cardiaques

Do not take amitriptyline if you have recently had a heart attack or have certain heart rhythm disorders (such as heart block), as it can affect the electrical signals in your heart.

Alcool

You must avoid or strictly limit alcohol while taking these medicines. Both amitriptyline and tizanidine cause drowsiness and dizziness; alcohol significantly increases these effects, which can lead to dangerous levels of sedation, impaired coordination, and breathing difficulties.

Caféine (Café, Thé, Boissons Énergisantes)

Caffeine can interfere with how your body breaks down tizanidine. This can lead to higher levels of the medicine in your blood, increasing the risk of side effects like very low blood pressure, a slow heart rate, or extreme drowsiness.

Taking multiple medicines? Our Vérificateur d'Interactions Médicamenteuses helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Avertissement

Ces informations sont fournies à des fins éducatives générales uniquement et ne doivent pas être considérées comme un substitut aux conseils médicaux professionnels. Consultez toujours votre médecin généraliste, votre pharmacien ou un autre professionnel de santé qualifié avant de prendre des décisions concernant vos médicaments. Les circonstances individuelles peuvent varier, et seul un professionnel de santé connaissant votre historique médical peut fournir des conseils personnalisés.