Puis-je prendre Amitriptyline et Zopiclone ensemble ?

You should only take these two medicines together if your doctor is specifically aware you are using both and has told you to do so.

Taking amitriptyline et zopiclone together can make you feel extremely drowsy, dizzy, and confused.

Pourquoi cela se produit

Both medicines work by slowing down the activity in your central nervous system (your brain and nerves).

Amitriptyline is a tricyclic antidepressant with sedative properties, and zopiclone is a 'Z-drug' used for sleep.

When used together, their sedative effects add up (an additive effect), making the overall impact much stronger than taking either medicine alone.

You may be experiencing an interaction between amitriptyline and zopiclone if:

• You feel excessively sleepy, drowsy, or sedated during the day.

• You experience confusion, dizziness, or difficulty concentrating.

• Vous remarquez des difficultés de coordination ou d'équilibre, ce qui augmente le risque de chute.

• You have memory problems or unusual behaviour.

• Breathing becomes slower or shallower than usual, especially at night.

• Les symptômes apparaissent peu de temps après avoir pris les deux médicaments ensemble.
  

Si vous présentez l'un des symptômes ci-dessus, vous devriez :

• Consultez votre médecin ou votre pharmacien pour des conseils sur l'utilisation sûre et la posologie.

• Do not stop amitriptyline or zopiclone suddenly unless instructed by a healthcare professional.

• Seek urgent medical help if you experience severe drowsiness, breathing difficulties, or confusion.

• Évitez de conduire ou de faire fonctionner des machines jusqu'à ce que vous sachiez comment la combinaison vous affecte.

• Informez votre professionnel de santé de tous les autres médicaments et compléments que vous prenez.

If you are prescribed both, take them exactly as directed, usually right before bed. Do not drive, operate machinery, or drink any alcohol while using this combination. If you feel excessively sleepy the next day or have trouble breathing, contact your doctor immediately.

Idées suicidaires et changements d'humeur

L'amitriptyline peut augmenter le risque de pensées suicidaires ou d'automutilation, en particulier lors du début du traitement ou du changement de doses. Consultez immédiatement un médecin si votre humeur change ou si vous vous sentez déprimé.

Drowsiness and coordination

Both medicines cause significant drowsiness and impaired coordination. This effect is much stronger when they are taken together, significantly increasing the risk of falls and accidents. Do not drive or operate machinery until you know how they affect you.

Complex sleep behaviours

Zopiclone can cause you to get out of bed while not fully awake and do activities you do not remember (such as sleep-walking, driving, or preparing food). Stop taking it immediately if this happens.

Troubles du rythme cardiaque

Amitriptyline can affect your heart rhythm. It must be used with extreme caution if you have a history of heart disease, particularly a recent heart attack or an irregular heartbeat (arrhythmia).

Alcool

You must avoid or strictly limit alcohol while taking these medicines. Both amitriptyline and zopiclone cause drowsiness and slow your reactions. Alcohol significantly increases these effects, which can lead to dangerous levels of sedation, breathing difficulties, and an increased risk of falls or accidents.

Caféine (Café, thé, boissons énergisantes)

Caffeine is a stimulant that works against the sedative effects of zopiclone. Consuming caffeine, especially in the evening, can make zopiclone less effective at helping you sleep.

Taking multiple medicines? Our Vérificateur d'Interactions Médicamenteuses helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Avertissement

Ces informations sont fournies à des fins éducatives générales uniquement et ne doivent pas être considérées comme un substitut aux conseils médicaux professionnels. Consultez toujours votre médecin généraliste, votre pharmacien ou un autre professionnel de santé qualifié avant de prendre des décisions concernant vos médicaments. Les circonstances individuelles peuvent varier, et seul un professionnel de santé connaissant votre historique médical peut fournir des conseils personnalisés.