Can I take Amlodepine and Sentraline together?
Drug interaction guide
Originally published 25 Jan 2026
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Taking amlodipine and sertraline together may cause your blood pressure to drop lower than intended. This can make you feel dizzy, lightheaded, or faint, especially when standing up quickly. There is also a very small risk of affecting your heart rhythm.
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Why this happens
Both medications can lower blood pressure (amlodipine is a calcium channel blocker for blood pressure, and sertraline can sometimes lower pressure as a side effect). Additionally, both drugs are processed by the liver; sertraline may slightly slow down the breakdown of amlodipine, leading to higher levels of it in your system.
What you should do
It is usually safe to take these together, but you should monitor your blood pressure regularly. Move slowly when standing up from a sitting or lying position. If you feel very dizzy, develop a racing heartbeat, or faint, contact your GP.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Clause de non-responsabilité
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historique de l'article
Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.
25 janvier 2026 | Publié à l'origine
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