Can I take Anastrozole and Simvastatin together?
Drug interaction guide
Originally published 25 Jan 2026
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There is no known direct interaction between anastrozole and simvastatin. However, both medications can independently cause muscle aches or joint pain as side effects. Taking them together might make it more difficult to determine which medicine is causing these symptoms if they occur.
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Why this happens
Anastrozole is an aromatase inhibitor used for breast cancer, and simvastatin is a statin used for cholesterol. They are processed by different pathways in the liver and do not interfere with how the body absorbs or removes the other. While they do not interact directly, they share a similar side-effect profile regarding muscle and joint discomfort.
What you should do
You can safely take these two medicines together. If you experience any new or worsening muscle pain, tenderness, or weakness, you should contact your doctor. It is helpful to keep a record of when any symptoms started so your doctor can determine which medication might be responsible.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Clause de non-responsabilité
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historique de l'article
Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.
25 janvier 2026 | Publié à l'origine
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