Puis-je prendre Apixaban et Empagliflozin ensemble ?

Pourquoi cela se produit

Apixaban (a blood thinner) and empagliflozin (a diabetes medication) are processed by different pathways in the body. Apixaban is mainly broken down by specific liver enzymes (CYP3A4) and a transport protein (P-gp), while empagliflozin is processed through a different liver pathway (glucuronidation) and removed by the kidneys. They do not interfere with how each other works or how they are cleared from the system.

You can continue taking both medications as prescribed by your doctor. However, because empagliflozin can have a mild diuretic effect (making you pass more urine), ensure you stay well-hydrated. Always inform your healthcare provider if you notice any unusual bruising or bleeding, which is a general precaution when taking any blood thinner like apixaban.

Surgery or dental procedures

You must tell your surgeon or dentist you are taking apixaban before any procedure, as it significantly increases your risk of bleeding and may need to be stopped temporarily.

Diabetic Ketoacidosis (DKA)

Empagliflozin can cause a serious condition called ketoacidosis even if your blood sugar levels are near normal. Seek urgent medical help if you experience nausea, vomiting, or stomach pain.

Fournier's gangrene - empagliflozin

Seek immediate medical attention if you experience pain, tenderness, redness, or swelling in the genital or anal area, accompanied by fever or malaise.

Alcool

While there is no direct chemical interaction, you should be cautious. For apixaban, heavy drinking increases the risk of stomach bleeding. For empagliflozin, alcohol can increase the risk of dehydration, low blood sugar (hypoglycaemia), and a serious condition called ketoacidosis. Stick to moderate amounts.

Taking multiple medicines? Our Vérificateur d'Interactions Médicamenteuses helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Avertissement

Ces informations sont fournies à des fins éducatives générales uniquement et ne doivent pas être considérées comme un substitut aux conseils médicaux professionnels. Consultez toujours votre médecin généraliste, votre pharmacien ou un autre professionnel de santé qualifié avant de prendre des décisions concernant vos médicaments. Les circonstances individuelles peuvent varier, et seul un professionnel de santé connaissant votre historique médical peut fournir des conseils personnalisés.