Can I take Chaga and Maitake together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
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Taking chaga and maitake together may increase the risk of your blood sugar dropping too low (hypoglycaemia) or your blood becoming too thin, which can lead to easier bruising or bleeding.
Why this happens
Both chaga and maitake mushrooms have natural properties that can lower blood sugar levels and slow down blood clotting. When used together, these effects can add up (an additive effect), making them stronger than if you took either one alone.
What you should do
Use this combination with caution. If you have diabetes or take blood-thinning medications (like warfarin or aspirin), you should speak to your doctor before taking these supplements. Monitor your blood sugar levels closely and watch for signs of easy bruising or bleeding gums. Stop taking both at least two weeks before any scheduled surgery.
Important precautions
Kidney disease or history of kidney stones
Chaga is extremely high in oxalates, which can cause permanent kidney damage or acute kidney failure, especially in those with existing renal issues.
Diabetes
Both mushrooms can significantly lower blood sugar levels, increasing the risk of hypoglycaemia (dangerously low blood sugar) if you are taking insulin or other diabetes medications.
Autoimmune diseases (e.g., Lupus, MS, Rheumatoid Arthritis)
Chaga can stimulate the immune system, which may worsen symptoms of autoimmune conditions or interfere with immunosuppressant medications.
Bleeding disorders or upcoming surgery
These mushrooms have anti-platelet effects and can thin the blood. This increases the risk of bruising and excessive bleeding; they must be stopped at least 2 weeks before any scheduled surgery.
Food and drink warnings
Alcohol
Chaga contains high levels of oxalates. Combining it with alcohol may increase the risk of kidney stones or kidney stress, as both substances can affect renal function. Use with caution.
Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
Article also available in English, German, Spanish, French, Italian, Portuguese, Hindi, Hebrew, Arabic, and Swedish.
25 Jan 2026 | Originally published

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