Can I take Bisoprolol and Metformin together?
Drug interaction guide
Originally published 25 Jan 2026
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Bisoprolol can hide the warning signs of low blood sugar (hypoglycaemia). It may also slightly change how your body manages blood sugar levels, potentially making metformin less effective or increasing the risk of a 'hypo'.
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Why this happens
Bisoprolol is a beta-blocker. It works by slowing the heart rate and blocking certain stress hormones. These same hormones are what cause the 'shaky' or 'racing heart' feelings that warn you when your blood sugar is too low. Additionally, beta-blockers can interfere with the body's natural process of releasing glucose into the blood.
What you should do
You can take these medicines together, but you should monitor your blood sugar levels more closely, especially when starting or changing doses. Be aware that you might not feel the usual 'racing heart' if your sugar drops; instead, look out for signs like sweating, hunger, or confusion. If you notice unusual changes in your blood sugar readings, speak to your doctor.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Clause de non-responsabilité
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historique de l'article
Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.
25 janvier 2026 | Publié à l'origine
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