Can I take Bisoprolol and Simvastatin together?
Drug interaction guide
Originally published 25 Jan 2026
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There is no direct interaction between bisoprolol and simvastatin. However, both medications can occasionally cause muscle-related side effects, such as weakness or fatigue. While rare, taking them together might slightly increase the chance of feeling tired or having low energy.
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Why this happens
Bisoprolol is a beta-blocker used for heart rate and blood pressure, while simvastatin is a statin used for cholesterol. They are processed by different pathways in the liver and do not interfere with how the other is absorbed or removed from the body.
What you should do
You can safely take these two medicines together. It is a very common combination for heart health. If you experience unusual muscle pain, tenderness, or weakness (which can be a side effect of simvastatin), or extreme tiredness, mention it to your doctor at your next check-up.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Clause de non-responsabilité
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historique de l'article
Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.
25 janvier 2026 | Publié à l'origine
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