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Puis-je prendre Estradot et un traitement hormonal substitutif ensemble ?

Guide d'interaction médicamenteuse

Estradot is a brand name for a type of Hormone Replacement Therapy (HRT) containing oestradiol. Taking Estradot alongside other HRT medications that contain oestrogen is essentially taking a double dose of the same medication. This can lead to an overdose of oestrogen, causing side effects like breast tenderness, nausea, headaches, and an increased risk of blood clots.

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Pourquoi cela se produit

Estradot and other oestrogen-based HRT products have 'additive' effects. Because they contain the same or similar active ingredients, using them together increases the total amount of hormone in your bloodstream beyond the recommended therapeutic level.

Do not use Estradot with any other oestrogen-containing HRT unless specifically instructed by a specialist. If you are already using an HRT patch, gel, or tablet, speak to your doctor or pharmacist before starting Estradot to ensure you are not duplicating your treatment.

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History of blood clots (VTE) or breast cancer

You must not use this treatment if you have ever had a blood clot in a vein (thrombosis), a pulmonary embolism, or if you have ever had breast cancer, as HRT can significantly increase the risk of these conditions recurring.

Utérus intact

If you still have your womb, using Estradot (oestrogen) alone increases the risk of cancer of the womb lining. You must also take a progestogen medicine to protect your womb lining unless you have had a hysterectomy.

Application site selection

Never apply the patch on or near the breasts. It should only be applied to the lower body (usually the buttocks or hips) to avoid increasing the risk of breast-related complications.

Jus de pamplemousse

Grapefruit juice can interfere with the enzymes that break down oestrogen in your body. This may lead to higher levels of the hormone in your bloodstream, potentially increasing the risk of side effects like breast tenderness, nausea, or bloating. While a small amount is unlikely to cause harm, it is best to avoid consuming large quantities.

Alcool

Drinking alcohol while using HRT can cause a temporary spike in your oestrogen levels. Long-term, heavy alcohol consumption combined with HRT may also slightly increase the risk of breast cancer compared to HRT use alone. It is advisable to stay within the recommended UK low-risk drinking guidelines (no more than 14 units per week).

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Taking multiple medicines? Our Vérificateur d'Interactions Médicamenteuses helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Avertissement

Ces informations sont fournies à des fins éducatives générales uniquement et ne doivent pas être considérées comme un substitut aux conseils médicaux professionnels. Consultez toujours votre médecin généraliste, votre pharmacien ou un autre professionnel de santé qualifié avant de prendre des décisions concernant vos médicaments. Les circonstances individuelles peuvent varier, et seul un professionnel de santé connaissant votre historique médical peut fournir des conseils personnalisés.

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Historique de l'article

Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.

  • 25 janv. 2026 | Publié à l'origine
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