Puis-je prendre Lansoprazole et Quétiapine ensemble ?

Pourquoi cela se produit

Lansoprazole reduces stomach acid, which can change how quetiapine dissolves and is absorbed. By making the stomach less acidic, lansoprazole may slightly lower the amount of quetiapine that gets into your bloodstream. Additionally, both medications have the potential to affect the electrical activity of the heart (prolonging the QT interval), and using them together may increase this risk.

You should speak to your doctor before taking these together. They may want to perform a simple heart trace (ECG) to check your heart rhythm or monitor your symptoms more closely. Seek immediate medical help if you feel dizzy, faint, or notice a fluttering or pounding heartbeat.

Suicidal thoughts and self-harm

Quetiapine can increase the risk of suicidal thoughts or self-harm, particularly in young adults (under 25). You must tell someone you trust or seek medical help immediately if your mood changes or you have thoughts of hurting yourself.

Troubles du rythme cardiaque (syndrome du QT long)

Quetiapine can affect your heart rhythm. You must tell your doctor if you have a history of heart disease, slow heart rate, or if you are taking other medicines that can cause 'QT prolongation'.

Diarrhée sévère

Le lansoprazole peut augmenter votre risque d'infections intestinales graves. Si vous développez une diarrhée aqueuse sévère ou persistante, ou de la fièvre, contactez immédiatement votre médecin et ne prenez pas de médicament anti-diarrhéique.

Lupus (LES) ou réactions cutanées

Contactez votre médecin si vous développez une éruption cutanée, surtout dans les zones exposées au soleil, car le lansoprazole peut provoquer une réaction cutanée auto-immune rare mais grave.

Drowsiness and impaired coordination

Quetiapine causes significant drowsiness and can affect your balance. Do not drive or operate machinery until you know how it affects you, and be careful to avoid falls, especially when getting up from a sitting or lying position.

Dementia-related psychosis

Quetiapine must not be used to treat elderly patients with dementia-related psychosis, as it significantly increases the risk of stroke and death in this group.

Diabetes and high blood sugar

Quetiapine can cause a significant increase in blood sugar levels, which can lead to or worsen diabetes. You should monitor for symptoms like extreme thirst or frequent urination.

Alcool

It is best to avoid or strictly limit alcohol while taking lansoprazole. Alcohol increases the amount of acid your stomach produces, which can make your symptoms worse and counteract the effects of the medicine.

It is best to avoid or strictly limit alcohol while taking quetiapine. Combining the two can significantly increase drowsiness and dizziness, making you more likely to fall or have an accident. It can also impair your coordination and judgement.

Alimentation (Timing)

Lansoprazole works best if you take it at least 30 minutes before food. Taking it with or after food can make it less effective at reducing stomach acid.

Jus de pamplemousse

Avoid drinking grapefruit juice or eating grapefruit while taking quetiapine. Grapefruit can increase the amount of quetiapine in your blood, which makes side effects much more likely and potentially more severe.

Caféine (Café, Thé, Boissons Énergisantes)

Caffeine can interfere with how quetiapine works. It may reduce the effectiveness of the medicine or worsen certain side effects like restlessness. If you consume a lot of caffeine, talk to your doctor before making any sudden changes to your intake, as this can also affect your medicine levels.

Lansoprazole is often prescribed for acid reflux. Caffeine can trigger or worsen reflux symptoms by relaxing the muscle at the base of the food pipe, which may make your medicine less effective at managing your symptoms.

Repas riches en graisses

If you are taking the extended-release (XL) version of quetiapine, you should avoid taking it with a very heavy or high-fat meal. This can cause the medicine to be absorbed into your system too quickly (known as 'dose dumping'), which increases the risk of side effects. It is usually best to take it without food or with a light snack.

Taking multiple medicines? Our Vérificateur d'Interactions Médicamenteuses helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Avertissement

Ces informations sont fournies à des fins éducatives générales uniquement et ne doivent pas être considérées comme un substitut aux conseils médicaux professionnels. Consultez toujours votre médecin généraliste, votre pharmacien ou un autre professionnel de santé qualifié avant de prendre des décisions concernant vos médicaments. Les circonstances individuelles peuvent varier, et seul un professionnel de santé connaissant votre historique médical peut fournir des conseils personnalisés.