Can I take Naproxen and Oxycodone together?

Pourquoi cela se produit

Naproxen is a non-steroidal anti-inflammatory drug (NSAID) that reduces protective chemicals in the stomach lining and affects blood flow to the kidneys. Oxycodone is an opioid painkiller. While they work in different ways to stop pain (additive effect), taking them together does not change how the body breaks them down, but it does increase the overall burden on your internal organs, particularly the digestive system and kidneys.

You can take these medicines together if your doctor has specifically prescribed both, but you must use caution. Always take naproxen with food or a glass of milk to protect your stomach. Drink plenty of water to help your kidneys. If you notice any signs of stomach bleeding (such as black, tarry stools or coffee-ground-like vomit) or severe indigestion, stop taking the naproxen and contact your doctor immediately. Do not take more than the recommended dose of either medication.

Opioid addiction and respiratory depression

Oxycodone is highly addictive and can lead to dependence. Taking too much, or mixing it with alcohol or benzodiazepines, can cause dangerously slow or shallow breathing which can be fatal.

Asthme

Ne prenez pas de naproxène si vous souffrez d'asthme sensible à l'aspirine ou à d'autres AINS, car cela peut déclencher une crise d'asthme potentiellement mortelle ou de graves difficultés respiratoires.

Ulcères d'estomac ou saignements

Naproxen can cause serious stomach ulcers and internal bleeding. This risk is higher if you have had ulcers before, are over 65, or take other blood-thinning medicines. Stop taking it and see a doctor immediately if you have black, tarry stools or vomit blood.

Grossesse (troisième trimestre)

Ne prenez pas de naproxène si vous êtes enceinte de plus de 20 semaines. Cela peut provoquer de graves problèmes rénaux ou cardiaques chez le bébé à naître et peut entraîner des complications lors de l'accouchement.

Alcool

It is best to avoid or strictly limit alcohol when taking oxycodone. Combining alcohol with this medicine significantly increases the risk of dangerous side effects, such as severe drowsiness, breathing difficulties, and a potentially fatal overdose.

It is best to avoid or strictly limit alcohol while taking naproxen. Both alcohol and naproxen can irritate the lining of your stomach; combining them significantly increases your risk of developing stomach ulcers or internal bleeding.

Jus de pamplemousse

Avoid drinking grapefruit juice or eating grapefruit while taking oxycodone. Grapefruit can interfere with how your body breaks down the medicine, leading to higher levels of the drug in your blood and increasing the risk of serious side effects.

Nourriture (Général)

Vous devriez prendre de l'ibuprofène naproxène avec un repas ou juste après un repas ou une collation. Cela aide à protéger la muqueuse de votre estomac et réduit le risque de dyspepsie ou de douleurs d'estomac.

Taking multiple medicines? Our Vérificateur d'Interactions Médicamenteuses helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Avertissement

Ces informations sont fournies à des fins éducatives générales uniquement et ne doivent pas être considérées comme un substitut aux conseils médicaux professionnels. Consultez toujours votre médecin généraliste, votre pharmacien ou un autre professionnel de santé qualifié avant de prendre des décisions concernant vos médicaments. Les circonstances individuelles peuvent varier, et seul un professionnel de santé connaissant votre historique médical peut fournir des conseils personnalisés.