Clobazam pour l'épilepsie
Frisium
Révision par Sid DajaniDernière mise à jour par Michael Stewart, MRPharmSDernière mise à jour le 17 octobre 2022
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Clobazam is prescribed to treat epilepsy. It can cause you to feel sleepy, particularly when you first start taking it, and it is likely to affect your reactions. These effects can last into the following day.
Continue to take clobazam regularly until your doctor tells you to stop. You must not stop taking it without speaking with your doctor first, as stopping suddenly will cause problems.
Do not drink alcohol whilst you are on clobazam.
Dans cet article :
Poursuivre la lecture ci-dessous
About clobazam for epilepsy
Type de médicament | A benzodiazepine anti-epileptic medicine |
Utilisé pour | Epilepsie |
Également appelé | Frisium®; Perizam®; Tapclob®; Zacco® |
Disponible en | Comprimés et médicaments liquides oraux |
Clobazam is used alongside other medicines to treat epileptic disease and seizures. It can be taken both by adults and by older children.
If you have epilepsy, it means that you have had more than one unexplained fit (seizure). A seizure is a short episode of symptoms caused by a burst of abnormal electrical activity in your brain. Different parts of the brain control different functions of your body, so the symptoms that occur during a seizure will depend on where the abnormal burst of electrical activity occurs. Symptoms that may occur during a seizure can affect your muscles, sensations, behaviour, emotions, consciousness, or a combination of these. The seizures can be prevented in most people by suitable anti-epileptic medication.
Clobazam controls the symptoms of seizures by stabilising the electrical activity of your brain, which prevents the seizures from occurring. It also relaxes muscles that stiffen (contract) during a seizure. This means that the numbers of seizures are reduced, and those that do occur, are less severe.
Before taking clobazam
Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking clobazam it is important that your doctor knows:
Si vous êtes enceinte, si vous essayez d'avoir un enfant ou si vous allaitez.
Si vous avez des problèmes respiratoires.
Si vous avez des problèmes de fonctionnement du foie ou des reins.
Si vous avez un problème de santé mentale. Il peut s'agir de psychoses, de dépressions, de troubles obsessionnels, de phobies ou de troubles de la personnalité.
Si vous avez déjà souffert d'une dépendance à la drogue ou à l'alcool.
Si vous souffrez d'une maladie provoquant une faiblesse musculaire sévère, appelée myasthénie grave.
If you have been told you have spinal or cerebellar ataxia. These are conditions where you have difficulty controlling your movements - you may become shaky and unsteady, have slurred speech or rapid eye movements.
Si vous avez déjà eu une réaction allergique à un médicament.
Si vous prenez ou utilisez d'autres médicaments. Cela comprend tous les médicaments que vous prenez et qui sont disponibles sans ordonnance, ainsi que les médicaments à base de plantes et les médicaments complémentaires.
Poursuivre la lecture ci-dessous
How to take clobazam
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about clobazam, and it will also provide you with a full list of the side-effects which you could experience from taking it.
Take clobazam exactly as your doctor tells you to - the dose will be individualised to suit your needs. You will be advised to take a small dose when you first start taking it, and then to increase your dose over a few weeks as your body gets used to it. Your doctor or pharmacist will explain this to you, and the directions will also be printed on the label of the pack to remind you about what the doctor said to you.
Clobazam is usually taken as a once-daily dose at bedtime, although as your dose increases you may be asked to take it divided into two smaller doses. Try to take it at the same time(s) each day, as this will help you to remember to take your doses regularly.
You can take clobazam either with or without food. Swallow the tablet(s) with a drink of water. If you have been given liquid medicine, shake the bottle gently before measuring out a dose.
If you forget to take a dose, take it as soon as you remember. Try to take the correct number of doses each day, but do not take two doses together to make up for a forgotten dose.
Clobazam is available as tablets and as liquid medicine. Your treatment could be affected by switching between different forms and brands of the medicine. If this is the case for you, each time you collect a new supply, check the label to make sure it is the same as you have had before or ask your pharmacist to check it out for you.
Tirer le meilleur parti de votre traitement
Essayez de vous rendre à vos rendez-vous réguliers avec votre médecin. Il pourra ainsi vérifier vos progrès.
Lorsque vous commencez un nouveau traitement contre l'épilepsie, il se peut que le nombre ou le type de crises change. Votre médecin vous conseillera à ce sujet.
Clobazam can make you feel sleepy, especially when you first start treatment. Do not drink alcohol while you are on clobazam as it will increase the likelihood that you experience this side-effect.
Products containing cannabidiol, or CBD, can also make you more likely to feel sleepy when taking clobazam. You should avoid using any supplements or non-medicinal products containing CBD.
Pendant que vous êtes traité pour une épilepsie, il existe un faible risque que vous développiez des changements d'humeur, des pensées angoissantes et des envies de suicide. Si cela se produit, vous devez en parler immédiatement à votre médecin.
People with epilepsy must stop driving at first. Your doctor will advise you about if and when it may be possible for you to start driving again. This will usually be after a year free of seizures. If you are permitted to drive, please be aware that clobazam is likely to affect your reactions and ability to drive. It is an offence to drive while your reactions are impaired. Please also be aware that the effects of clobazam can last into the following day. Even if your driving ability is not impaired, should you drive, you are advised to carry with you some evidence that the medicine has been prescribed for you - a repeat prescription form or a patient information leaflet from the pack is generally considered suitable.
Taking clobazam over a period of time can make you become tolerant to it. If this happens, it will not be as effective for you as it once was. If you think this is happening to you, please discuss it with your doctor.
Taking benzodiazepines like clobazam can lead to the development of dependence, in which your body comes to rely on the medicine. If you are concerned about this, you should discuss it with your doctor.
Many anti-epileptic medicines can harm an unborn child. If you are a woman, make sure you have discussed with your doctor which types of contraception are suitable for you and your partner. If you want to have a family, discuss this with your doctor so that you can be given advice from a specialist before you become pregnant.
Si vous devez subir une opération ou un traitement dentaire, indiquez à la personne chargée du traitement les médicaments que vous prenez.
You need to take clobazam regularly every day. Do not stop taking it until your doctor tells you to stop. Stopping treatment suddenly can cause problems and your doctor will want you to reduce your dose gradually when this becomes necessary.
Poursuivre la lecture ci-dessous
Can clobazam cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the more common ones associated with clobazam. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common clobazam side-effects | Que puis-je faire si je suis confronté à cette situation ? |
Sentiment de somnolence, de faiblesse ou d'étourdissement (ces symptômes peuvent persister le lendemain) | Ne conduisez pas et n'utilisez pas d'outils ou de machines lorsque vous êtes affecté. Ne pas boire d'alcool |
Bouche sèche | Take frequent sips of water or try chewing sugar-free chewing gum or sucking sugar-free sweets |
Constipation | Drink plenty of water and try to eat a balanced diet with plenty of fruit and vegetables. If this becomes troublesome, let your doctor know |
Feeling sick (nausea), feeling unsteady, poor co-ordination, unusual eye movements, poor concentration, slow speech, feeling forgetful or confused, reduced appetite | Si l'une d'entre elles devient gênante, parlez-en à votre médecin. |
Feeling aggressive (particularly in children) | Let your doctor know if this happens |
Maux de tête | Buvez beaucoup d'eau et demandez à un pharmacien de vous recommander un analgésique adapté. Si les maux de tête persistent, prévenez votre médecin |
Si vous ressentez d'autres symptômes qui pourraient être dus au médicament, demandez conseil à votre médecin ou à votre pharmacien.
How to store clobazam
Conservez tous les médicaments hors de la portée et de la vue des enfants.
Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.
Once a bottle of Tapclob® or Perizam® Oral Suspension has been opened it will keep for 28 days. Zacco® Oral suspension will keep for 60 days after first opening. After this time, make sure you have a fresh supply of medicine.
Informations importantes sur tous les médicaments
Informations importantes sur tous les médicaments
Never take more than the prescribed dose. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty, so the doctor knows what has been taken.
Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.
Si vous achetez des médicaments, vérifiez auprès d'un pharmacien que vous pouvez les prendre en toute sécurité avec vos autres médicaments.
Ne gardez pas les médicaments périmés ou dont vous ne voulez plus. Apportez-les à votre pharmacie locale qui les éliminera pour vous.
Si vous avez des questions sur ce médicament, demandez à votre pharmacien.
Signaler les effets secondaires d'un médicament ou d'un vaccin
Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne sur le site web de la carte jaune.
Autres lectures et références
- Manufacturer's PIL, Frisium® Tablets 10 mg; Sanofi, The electronic Medicines Compendium. Dated July 2021.
- Manufacturer's PIL, Perizam 2 mg/ml Oral Suspension; Rosemont Pharmaceuticals Ltd, The electronic Medicines Compendium. Dated October 2020.
- Médicaments Complet BNF 89ème éditionBritish Medical Association et Royal Pharmaceutical Society of Great Britain, Londres.
Historique de l'article
Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.
Prochaine révision prévue : 16 Oct 2025
17 Oct 2022 | Dernière version
7 Jun 2013 | Publié à l'origine
Auteur: :
Helen Allen, MPharm

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