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Injection d'Olanzapine à action prolongée

Zypadhera

Olanzapine long-acting injection will be given to you by your clinic doctor or nurse every 2-4 weeks.

The injection may cause you to feel sleepy or dizzy for a few hours afterwards.

If you miss an appointment for an injection, make another appointment as soon as possible.

There are a number of side-effects which you could experience from the treatment. If you are concerned about any, you should discuss them with your doctor.

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About olanzapine long-acting injection

Type de médicament

An antipsychotic injection

Utilisé pour

Maintenance of symptom control in adults with schizophrenia and other similar mental health problems

Aussi appelé

Zypadhera® (olanzapine embonate)

Disponible sous forme de

Long-acting depot injection

Olanzapine belongs to a group of medicines called antipsychotics. You will have been prescribed it to maintain symptom control of la schizophrénie.

Schizophrenia is a mental health condition that causes disordered ideas, beliefs and experiences. Symptoms of schizophrenia include hearing, seeing, or sensing things that are not real, having mistaken beliefs, feeling unusually suspicious, and becoming withdrawn. Olanzapine is used to relieve the symptoms of schizophrenia and other similar mental health problems. It works on the balance of chemical substances in your brain.

Long-acting, or 'depot', injections are used once your symptoms have been eased by taking tablets. The injection slowly releases olanzapine into your body and is given either every two weeks, or every four weeks. The main advantage of a depot injection is that you do not have to remember to take tablets every day.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start having olanzapine long-acting injections, it is important that your doctor knows:

  • Si vous êtes enceinte ou si vous allaitez.

  • Si vous avez une maladie cardiaque ou une maladie des vaisseaux sanguins.

  • Si vous avez des problèmes avec le fonctionnement de votre foie, ou si vous avez des problèmes avec le fonctionnement de vos reins.

  • If you have prostate problems.

  • Si vous avez des problèmes de respiration.

  • If you have any of the following: épilepsie, diabète (diabète sucré), dépression, la maladie de Parkinson, raised pressure in your eye (glaucoma) or a condition which causes muscle weakness, called myasthenia gravis.

  • If you have ever had yellowing of your skin or the whites of your eyes (jaunisse).

  • If you have a blood or bone marrow disorder.

  • If you are very constipated or think you may have a blockage in your bowel.

  • Si vous avez eu une réaction allergique à un médicament.

  • Si vous prenez ou utilisez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et complémentaires.

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  • Before you start the treatment, ask to read the manufacturer's printed information leaflet from inside the pack. The leaflet will give you more information about olanzapine, and it will also provide you with a full list of the side-effects which you could experience.

  • Olanzapine long-acting injection will be given to you in an outpatient clinic by a doctor or nurse. The injection is given into a muscle in your bottom (buttocks). As a routine, you will be asked to stay in the clinic where you can be observed for at least three hours after each injection. This is because it can make you feel tired or dizzy after it is given. You will be advised not to drive and not to use tools or machines for the remainder of the day.

  • You may be asked to continue taking your current tablets for a short while after you have had your first injection. This is because it can take a few weeks before you feel the full effect from the injection.

  • Treatment with olanzapine is usually long-term so that your symptoms don't return.

  • Your treatment will require careful monitoring to make sure that you get the best possible benefit from olanzapine. Keep your regular doctor's appointments so that you get your injections on time, and your progress can be checked. If you miss an appointment for an injection, contact the hospital to arrange for another appointment as soon as possible.

  • Olanzapine could cause your skin to become more sensitive to sunlight than normal. Avoid strong sunlight and sunbeds, and use a sun cream with a high sun protection factor even on bright but cloudy days.

  • If you drink alcohol, ask your doctor for advice about drinking while you are on olanzapine. Alcohol can increase the chance that you will experience side-effects and may not be advisable for you.

  • If you have diabetes you may need to check your blood sugar (glucose) more frequently, as olanzapine can affect the levels of sugar in your blood. Your doctor will advise you about this.

  • If you are having any dental treatment or an operation, tell the person carrying out the treatment that you have had an olanzapine injection. This is important because it may interfere with the anaesthetic you receive.

  • If you buy or take any 'over-the-counter' medicines, check with a pharmacist that they are suitable for you to take with olanzapine.

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Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the more common ones associated with olanzapine. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.

Very common olanzapine side-effects (these affect more than 1 in 10 people)


Que puis-je faire si je ressens cela ?

Feeling sleepy, tired or dizzy

Ne conduisez pas et n'utilisez pas d'outils ou de machines lorsque vous êtes affecté

Increased weight

Eat a well-balanced diet. Speak with your doctor if your weight becomes troublesome

Changes to some blood test results

Your doctor will monitor for these

Common olanzapine side-effects

(ces effets touchent moins de 1 personne sur 10)

Que puis-je faire si je ressens cela ?

Feeling restless

Parlez-en avec votre médecin

Pain at the site of the injection

This should not last long. If the area becomes red, swollen or 'lumpy', let your doctor know

Bouche sèche

Essayez de mâcher du chewing-gum sans sucre ou de sucer des bonbons sans sucre

Constipation

Drink plenty of water, and eat a well-balanced diet containing plenty of fruit, vegetables, and fibre

Unusual or uncontrollable muscle movements, shakiness

Parlez-en avec votre médecin

Increased appetite and weight, rash, feeling hot, reduced interest in sex, erectile dysfunction, aches and pains

Discutez-en avec votre médecin si l'un d'eux devient gênant

Important: if you experience symptoms such as muscle stiffness, a very high temperature, feeling confused or sweaty, a fast heartbeat, and urinary incontinence, you should contact your doctor immediately. These can be signs of a rare but serious condition known as neuroleptic malignant syndrome.

Si vous ressentez d'autres symptômes que vous pensez être liés à l'injection, consultez votre médecin ou votre pharmacien pour obtenir des conseils supplémentaires.

Informations importantes sur tous les médicaments

If you suspect that you have had an overdose of this medicine, go to the accident and emergency department of your local hospital at once.

Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.

Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.

Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.

Signaler les effets secondaires d'un médicament ou d'un vaccin

Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le site web Yellow Card.

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Lectures complémentaires et références

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Historique de l'article

Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.

  • Next review due: 11 Jun 2027
  • 12 Dec 2022 | Dernière version

    Dernière mise à jour par

    Michael Stewart, MRPharmS

    Revu par

    Sid Dajani
  • 20 Aug 2010 | Publié à l'origine

    Écrit par :

    Helen Allen, MPharm
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