Pilocarpine en comprimés
Salagen
Peer reviewed by Sid DajaniLast updated by Michael Stewart, MRPharmSLast updated 5 Feb 2025
Répond aux besoins du patient lignes directrices éditoriales
- TéléchargerTélécharger
- Partager
Take pilocarpine during a meal. Swallow the tablet with a large glass of water.
The tablets may reduce your ability to see clearly in poor lighting. Do not drive at night if you are affected.
The most common side-effects include headache, sweating, flu-like symptoms and passing urine more frequently.
Dans cet article :
Poursuivre la lecture ci-dessous
About pilocarpine
Type de médicament | A cholinergic medicine |
Utilisé pour | Dry mouth after radiotherapy; dry mouth and dry eyes in Sjögren's syndrome |
Également appelé | Salagen® |
Disponible en | Tablettes |
Pilocarpine is prescribed to relieve dry mouth (sometimes called xerostomia) brought on by radiotherapy to the head or neck.
Pilocarpine can also be used to relieve some of the symptoms of Sjögren's syndrome. Sjögren's syndrome can cause various symptoms, the most common being dry eyes and dry mouth. These symptoms are due to lack of secretions from glands in your body.
Pilocarpine tablets stimulate your glands to produce more saliva and tears.
Before taking pilocarpine
Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking pilocarpine it is important that your doctor knows:
Si vous êtes enceinte ou si vous allaitez.
Si vous souffrez d'une maladie cardiaque ou d'une maladie des vaisseaux sanguins.
If you have a problem with the way your kidneys work, or a problem with the way your liver works.
If you have asthma, COPD, or any other breathing problem.
If you have a stomach ulcer, gallstones, or a problem with your bile duct.
If you have an eye condition such as increased pressure in your eye (glaucoma), or inflammation of the iris of your eye (iritis).
If you get confused easily.
Si vous prenez ou utilisez d'autres médicaments. Cela comprend tous les médicaments que vous prenez et qui sont disponibles sans ordonnance, ainsi que les médicaments à base de plantes et les médicaments complémentaires.
Si vous avez déjà eu une réaction allergique à un médicament.
Poursuivre la lecture ci-dessous
How to take pilocarpine
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about pilocarpine, and will also provide you with a full list of side-effects which you could experience from taking it.
Your doctor will tell you how often to take the tablets - take them exactly as your doctor directs. As a guide:
If you are taking pilocarpine following radiotherapy, it is likely you will be prescribed one tablet three times daily to begin with. Take your doses during (or straight after) a meal, and make sure you take your last dose of the day with your evening meal.
If you are taking pilocarpine because you have Sjögren's syndrome, the usual dose is one tablet four times daily. Take a tablet with each of your three main meals, and also one at bedtime. Although these are the usual starting doses for people taking pilocarpine, your doctor may increase your dose if it is appropriate for you.
Every time you take a tablet, drink a large glass of water with it. This is to prevent you from becoming dehydrated, as pilocarpine can make you sweat more than usual.
If you forget to take a dose, take it as soon as you remember unless your next dose is due. If it is nearly time for your next dose, don't take the forgotten dose but instead wait and take the next dose as normal. Do not take two doses together to make up for the missed dose.
Tirer le meilleur parti de votre traitement
Essayez de vous rendre à vos rendez-vous réguliers avec votre médecin. Il pourra ainsi vérifier vos progrès.
If after taking pilocarpine for a couple of months you feel that your condition has not greatly improved, you should let your doctor know about this. Pilocarpine will not be effective if the glands in your mouth or eyes cannot be sufficiently stimulated to produce more saliva or tears.
If you are due to have an operation or any dental treatment, please tell the person carrying out the treatment that you are taking pilocarpine.
If you buy any medicines 'over the counter', check with a pharmacist that they are suitable for you to take alongside pilocarpine.
Poursuivre la lecture ci-dessous
Can pilocarpine cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains the most common ones associated with pilocarpine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any continue or become troublesome.
Common and very common pilocarpine side-effects (some can affect more than 1 in 10 people) | Que puis-je faire si je suis confronté à cette situation ? |
Maux de tête | Buvez beaucoup d'eau et demandez à votre pharmacien de vous recommander un analgésique adapté. Si les maux de tête persistent, prévenez votre médecin |
Increased sweating and flushing | Take care not to become overheated during exercise or hot weather. Drink several large glasses of water every day |
Blurred vision, eye irritation or pain, watery eyes | Do not drive and do not use tools or machines if you cannot see clearly (particularly at night or if you have difficulty seeing in poor lighting) |
Diarrhoea, constipation, tummy ache (abdominal pain) | Try to eat a well-balanced diet. Drink plenty of water |
Indigestion, feeling sick (nausea) or being sick (vomiting) | Eat simple foods - avoid rich or spicy meals |
Sensation de vertige ou de faiblesse | Sit down for a few minutes until you feel better. Do not drive and do not use tools or machines while affected |
Increased frequency of passing urine, high blood pressure, the sensation of having a 'thumping' heart (palpitations), flu-like symptoms, runny nose, allergic reactions such as skin rash and itchiness | Si l'un d'entre eux devient gênant, parlez-en à votre médecin. |
Si vous ressentez d'autres symptômes qui pourraient être dus aux comprimés, demandez conseil à votre médecin ou à votre pharmacien.
How to store pilocarpine
Conservez tous les médicaments hors de la portée et de la vue des enfants.
Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.
Informations importantes sur tous les médicaments
Informations importantes sur tous les médicaments
Ne dépassez jamais la dose prescrite. Si vous pensez que vous ou quelqu'un d'autre avez pris une dose excessive de ce médicament, rendez-vous au service des accidents et des urgences de votre hôpital local. Emportez la boîte avec vous, même si elle est vide.
Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.
Ne gardez pas les médicaments périmés ou dont vous ne voulez plus. Apportez-les à votre pharmacie locale qui les éliminera pour vous.
Si vous avez des questions sur ce médicament, demandez à votre pharmacien.
Signaler les effets secondaires d'un médicament ou d'un vaccin
Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne sur le site web de la carte jaune.
Autres lectures et références
- Manufacturer's PIL, Salagen® 5 mg Film Coated Tablets; Norgine Limited, The electronic Medicines Compendium. Dated April 2023.
- Médicaments Complet BNF 89ème éditionBritish Medical Association et Royal Pharmaceutical Society of Great Britain, Londres.
Historique de l'article
Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.
Prochaine révision prévue : 5 février 2028
5 Feb 2025 | Dernière version

Demandez, partagez, connectez-vous.
Parcourez les discussions, posez des questions et partagez vos expériences sur des centaines de sujets liés à la santé.

Vous ne vous sentez pas bien ?
Évaluez gratuitement vos symptômes en ligne