Can I take Lions mane and Reishi together?
Drug interaction guide
Originally published 24 Jan 2026
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Taking Lion's Mane and Reishi together is generally considered safe for most people. However, both mushrooms have mild blood-thinning properties and can lower blood sugar levels. When taken together, these effects might be slightly stronger, though they are unlikely to cause problems for healthy individuals.
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Why this happens
Both supplements contain bioactive compounds (like polysaccharides) that can interfere with how blood clots and how the body processes glucose. Combining them may have an additive effect on these processes.
What you should do
It is usually fine to take these together. However, if you are scheduled for surgery, stop taking both at least two weeks beforehand. If you have diabetes or take blood-thinning medication (like warfarin or aspirin), monitor your blood sugar and watch for unusual bruising or bleeding. Consult your GP before starting this combination if you have a pre-existing medical condition.
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Using other medicines?
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Clause de non-responsabilité
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historique de l'article
Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.
24 janvier 2026 | Publié à l'origine
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