maladie de Basedow
Dernière mise à jour 22 Dec 2025
Respecte les directives éditoriales
- TéléchargerTélécharger
- Partager
- Language
- Discussion
- Version audio
- Ajouter aux sources préférées sur Google
Graves' disease is a condition that affects the function of the thyroid, which is a butterfly-shaped gland in the lower neck. The thyroid makes hormones that help regulate a wide variety of critical body functions. For example, thyroid hormones influence growth and development, body temperature, heart rate, menstrual cycles, and weight. In people with Graves' disease, the thyroid is overactive and makes more hormones than the body needs. The condition usually appears in mid-adulthood, although it may occur at any age.
Description
Graves' disease is a condition that affects the function of the thyroid, which is a butterfly-shaped gland in the lower neck. The thyroid makes hormones that help regulate a wide variety of critical body functions. For example, thyroid hormones influence growth and development, body temperature, heart rate, menstrual cycles, and weight. In people with Graves' disease, the thyroid is overactive and makes more hormones than the body needs. The condition usually appears in mid-adulthood, although it may occur at any age.
Excess thyroid hormones can cause a variety of signs and symptoms. These include nervousness or anxiety, extreme tiredness (fatigue), a rapid and irregular heartbeat, hand tremors, frequent bowel movements or diarrhea, increased sweating and difficulty tolerating hot conditions, trouble sleeping, and weight loss in spite of an increased appetite. Affected women may have menstrual irregularities, such as an unusually light menstrual flow and infrequent periods. Some people with Graves' disease develop an enlargement of the thyroid called a goiter. Depending on its size, the enlarged thyroid can cause the neck to look swollen and may interfere with breathing and swallowing.
Between 25 and 50 percent of people with Graves' disease have eye abnormalities, which are known as Graves' ophthalmopathy. These eye problems can include swelling and inflammation, redness, dryness, puffy eyelids, and a gritty sensation like having sand or dirt in the eyes. Some people develop bulging of the eyes caused by inflammation of tissues behind the eyeball and "pulling back" (retraction) of the eyelids. Rarely, affected individuals have more serious eye problems, such as pain, double vision, and pinching (compression) of the optic nerve connecting the eye and the brain, which can cause vision loss.
A small percentage of people with Graves' disease develop a skin abnormality called pretibial myxedema or Graves' dermopathy. This abnormality causes the skin on the front of the lower legs and the tops of the feet to become thick, lumpy, and red. It is not usually painful.
Inheritance patterns
The source lists the following possible inheritance patterns: Pattern unknown. More than one pattern can apply in different cases.
Related genes
Other names
Autoimmune hyperthyroidism
Basedow disease
Basedow's disease
Exophthalmic goiter
maladie de Basedow
Toxic diffuse goiter
Related patient information and medicines
Patient information leaflet
la maladie oculaire thyroïdienne
It is usually (but not always) associated with an overactive thyroid gland (hyperthyroidism) - and most often with one particular cause of an overactive thyroid gland, Graves' disease (Graves ophthalmology disease). Thyroid eye disease is sometimes called other names such as thyroid ophthalmopathy, dysthyroid eye disease, Graves' ophthalmopathy or.
Patient information leaflet
Maladie inflammatoire de l'intestin
Inflammatory Bowel Disease (IBD) is a term used to describe people who either have either of the two main types of IBD (Crohn's disease and ulcerative colitis). Infections (especially upper respiratory et bowel infections) or taking non-steroidal anti-inflammatory des drogues (NSAIDs) can also aggravate symptoms. Causes of inflammatory bowel disease.
Patient information leaflet
Maladies liées à l'amiante
People exposed to asbestos peuvent develop diseases in later life. These most commonly affect the lungs but can also affect the lining of the tummy (abdomen). Some conditions - for example, mesothelioma or lung cancer - are more serious than others. This leaflet gives a brief overview of the diseases that are related to having an exposure to asbestos.
Patient information leaflet
Psoriasis des ongles
Psoriasis is a persistent (chronic) peau condition which tends to flare up from time to time. About half of the people who have psoriasis also have changes affecting their nails. Psoriatic nail disease is very variable in ap... Fungal nail infections also cause thickening of the nails. It is important to get the correct treatment as some.
Patient information leaflet
Évaluation du risque pour la santé cardiovasculaire
A événements cardiovasculaires health risk assessment provides an accurate estimate of your risk of developing cardiovascular disease (eg, angina, heart attack, stroke or peripheral arterial disease) over the following 10 years, and provides an opportunity for you to make any changes that will reduce this risk. If you already have a cardiovascular disease or.
Patient information leaflet
Plaque dentaire et maladie des gencives
A build-up of la plaque et tartar can lead to inflamed et infected gums. Mild gum disease is called gingivitis and is not usually serious. To help the dental team treat you safely i... This includes liver diseases, blood conditions (such as haemophilia) and medications including aspirin and anticoagulants aimer warfarin, rivaroxaban (Xarelto®) and.
Lectures complémentaires et références
- maladie de Basedow; MedlinePlus, National Library of Medicine.
- Eschler DC, Hasham A, Tomer Y. Cutting edge: the etiology of autoimmune thyroid diseases. Clin Rev Allergy Immunol. 2011 Oct;41(2):190-7. doi: 10.1007/s12016-010-8245-8.
- Hasham A, Tomer Y. Genetic and epigenetic mechanisms in thyroid autoimmunity. Immunol Res. 2012 Dec;54(1-3):204-13. doi: 10.1007/s12026-012-8302-x.
- Jacobson EM, Huber A, Tomer Y. The HLA gene complex in thyroid autoimmunity: from epidemiology to etiology. J Autoimmun. 2008 Feb-Mar;30(1-2):58-62. doi: 10.1016/j.jaut.2007.11.010. Epub 2008 Jan 4.
- Institut National du Diabète et des Maladies Digestives et Rénales
- Simmonds MJ, Gough SC. The search for the genetic contribution to autoimmune thyroid disease: the never ending story? Brief Funct Genomics. 2011 Mar;10(2):77-90. doi: 10.1093/bfgp/elq036.
- Tomer Y. Genetic susceptibility to autoimmune thyroid disease: past, present, and future. Thyroid. 2010 Jul;20(7):715-25. doi: 10.1089/thy.2010.1644.
Participez à la conversation
Partagez vos pensées ou expériences avec les autres dans notre communautés de patients.
Demandez, partagez, connectez-vous.
Parcourez les discussions, posez des questions et partagez vos expériences sur des centaines de sujets de santé.
Inscrivez-vous à la newsletter Patient
Votre dose hebdomadaire de conseils de santé clairs et fiables - rédigés pour vous aider à vous sentir informé, confiant et maître de la situation.
En vous abonnant, vous acceptez notre Politique de confidentialité. Vous pouvez vous désabonner à tout moment. Nous ne vendons jamais vos données.