cystatin C
Dernière mise à jour 11 Apr 2022
Respecte les directives éditoriales
- TéléchargerTélécharger
- Partager
- Language
- Discussion
- Version audio
- Ajouter aux sources préférées sur Google
La CST3 gene provides instructions for making a protein called cystatin C. This protein is part of a family of proteins called cysteine protease inhibitors that help control several types of chemical reactions by blocking (inhibiting) the activity of certain enzymes. Cystatin C inhibits the activity of enzymes called cathepsins that cut apart other proteins in order to break them down.
Normal function
La CST3 gene provides instructions for making a protein called cystatin C. This protein is part of a family of proteins called cysteine protease inhibitors that help control several types of chemical reactions by blocking (inhibiting) the activity of certain enzymes. Cystatin C inhibits the activity of enzymes called cathepsins that cut apart other proteins in order to break them down.
Cystatin C is found in biological fluids, such as blood. Its levels are especially high in the fluid that surrounds and protects the brain and spinal cord (the cerebrospinal fluid or CSF).
Conditions referring to this gene or chromosome
Other names
cystatin 3
cystatin-3
cystatin-C
cystatin-C precursor
CYTC_HUMAN
gamma-trace
neuroendocrine basic polypeptide
post-gamma-globulin
Related patient information and medicines
Patient information leaflet
Test sanguin de routine pour la fonction rénale
This is calculated from the blood creatinine level, sex, age, body weight, and sometimes also height. It is often used when prescribing drugs that are very sensitive to kidney function. Cystatin-C. Blood levels of cystatin-C can be used to estimate kidney function, in a similar way to creatinine. Cystatin-C is less affected by muscle mass than.
Patient information leaflet
Césarienne
A caesarean section (C-section) may be planned (elective caesarean section) or unplanned (including emergency or crash caesarean sections). Caesarean section is an operation in which a cut is made in your tummy (abdomen) and in the wall of your womb (uterus) so that your ba... The National Institute for Health and Care Excellence (NICE) have.
Patient information leaflet
Clostridioides difficile
It was known as Clostridium difficile until 2019. It lives harmlessly in the gut of many people. About 3 in 100 healthy adults and as many as 7 in 10 healthy babies have a number of C. difficile bacteria living in their gut. The number of C. difficile bacteria that live in the gut of healthy people is kept in check by all the other harmless.
Medicine leaflet
Comprimés d'acide ascorbique
Ascorbic acid is another name for vitamin C. One dose a day of 25-75 mg is sufficient to prevent vitamin C deficiency. Higher doses are sometimes prescribed by doctors to treat a condition called scurvy (althou... About ascorbic acid Type of medicine A vitamin Used for Preventing and treating vitamine C deficiency Also called Vitamin C, Ascur®,.
Medicine leaflet
Capsules de clindamycine pour infection
If you develop diarrhoea while you are taking clindamycin, you must contact your doctor for advice before you take any more doses. About clindamycine Type of medicine A lincosamide antibiotic Used for Treating infections Also called Dalacin® C Available as Capsules What is clindamycin used for. Clindamycin is an antibiotic that is used to treat.
Lectures complémentaires et références
- cystatin C; MedlinePlus, National Library of Medicine.
- Ghiso J, Jensson O, Frangione B. Amyloid fibrils in hereditary cerebral hemorrhage with amyloidosis of Icelandic type is a variant of gamma-trace basic protein (cystatin C). Proc Natl Acad Sci U S A. 1986 May;83(9):2974-8. doi: 10.1073/pnas.83.9.2974.
- Kolodziejczyk R, Michalska K, Hernandez-Santoyo A, Wahlbom M, Grubb A, Jaskolski M. Crystal structure of human cystatin C stabilized against amyloid formation. FEBS J. 2010 Apr;277(7):1726-37. doi: 10.1111/j.1742-4658.2010.07596.x. Epub 2010 Feb 19.
- Levy E, Jaskolski M, Grubb A. The role of cystatin C in cerebral amyloid angiopathy and stroke: cell biology and animal models. Brain Pathol. 2006 Jan;16(1):60-70. doi: 10.1111/j.1750-3639.2006.tb00562.x.
- Palsdottir A, Snorradottir AO, Thorsteinsson L. Hereditary cystatin C amyloid angiopathy: genetic, clinical, and pathological aspects. Brain Pathol. 2006 Jan;16(1):55-9. doi: 10.1111/j.1750-3639.2006.tb00561.x.
- Revesz T, Ghiso J, Lashley T, Plant G, Rostagno A, Frangione B, Holton JL. Cerebral amyloid angiopathies: a pathologic, biochemical, and genetic view. J Neuropathol Exp Neurol. 2003 Sep;62(9):885-98. doi: 10.1093/jnen/62.9.885.
- Revesz T, Holton JL, Lashley T, Plant G, Frangione B, Rostagno A, Ghiso J. Genetics and molecular pathogenesis of sporadic and hereditary cerebral amyloid angiopathies. Acta Neuropathol. 2009 Jul;118(1):115-30. doi: 10.1007/s00401-009-0501-8. Epub 2009 Feb 19.
Participez à la conversation
Partagez vos pensées ou expériences avec les autres dans notre communautés de patients.
Demandez, partagez, connectez-vous.
Parcourez les discussions, posez des questions et partagez vos expériences sur des centaines de sujets de santé.
Inscrivez-vous à la newsletter Patient
Votre dose hebdomadaire de conseils de santé clairs et fiables - rédigés pour vous aider à vous sentir informé, confiant et maître de la situation.
En vous abonnant, vous acceptez notre Politique de confidentialité. Vous pouvez vous désabonner à tout moment. Nous ne vendons jamais vos données.