Puis-je prendre Atorvastatine et Ézétimibe ensemble ?

Pourquoi cela se produit

Both medicines work in different ways to lower cholesterol (atorvastatin stops the liver from making it, while ezetimibe stops the gut from absorbing it). Because both drugs can independently affect muscle tissue, taking them together has an 'additive' effect, meaning the small risk associated with each drug is combined.

It is generally safe to take these together if prescribed by your doctor. You should monitor yourself for any unexplained muscle pain, tenderness, or weakness, especially when you first start the treatment or if your dose is increased. If you notice these symptoms, or if your urine becomes dark in colour, contact your doctor immediately.

Grossesse

You must not take these medicines if you are pregnant or planning to become pregnant, as they can cause serious harm to an unborn baby. Use effective contraception while taking these medicines.

Muscle disorders

Consultez immédiatement un médecin si vous ressentez des douleurs musculaires inexpliquées, une sensibilité ou une faiblesse. Dans de rares cas, cela peut entraîner une affection grave appelée rhabdomyolyse, qui provoque des lésions rénales.

Jus de pamplemousse

Grapefruit juice contains compounds that can increase the level of atorvastatin in your blood. This may increase your risk of side effects, such as muscle pain or damage. Avoid drinking large quantities (more than 1.2 litres per day), though it is safest to avoid it altogether or keep intake to very small amounts.

Alcool

While there is no direct 'chemical' interaction, both these medicines and alcohol can affect your liver. Drinking large amounts of alcohol regularly while taking these medicines can increase the risk of liver problems. It is best to stay within the recommended UK low-risk guidelines (no more than 14 units per week).

Taking multiple medicines? Our Vérificateur d'Interactions Médicamenteuses helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Avertissement

Ces informations sont fournies à des fins éducatives générales uniquement et ne doivent pas être considérées comme un substitut aux conseils médicaux professionnels. Consultez toujours votre médecin généraliste, votre pharmacien ou un autre professionnel de santé qualifié avant de prendre des décisions concernant vos médicaments. Les circonstances individuelles peuvent varier, et seul un professionnel de santé connaissant votre historique médical peut fournir des conseils personnalisés.