Can I take Calcium and Indapamide together?
Drug interaction guide
Originally published 25 Jan 2026
Répond aux besoins du patient lignes directrices éditoriales
- TéléchargerTélécharger
- Partager
- Langue
- Discussion
Taking calcium supplements with indapamide can lead to high levels of calcium in your blood (hypercalcaemia). This can make you feel thirsty, tired, or sick, and in some cases, it can affect your heart rhythm or kidney function.
Dans cet article :
Poursuivre la lecture ci-dessous
Why this happens
Indapamide is a 'water pill' (diuretic) that works by reducing the amount of calcium your kidneys get rid of in your urine. If you take extra calcium supplements at the same time, the calcium builds up in your body because it isn't being flushed out as usual.
What you should do
Speak to your doctor before taking calcium supplements if you are prescribed indapamide. Your doctor may want to monitor your blood calcium levels with regular blood tests. If you experience symptoms like extreme thirst, frequent urination, confusion, or nausea, contact your GP.
Poursuivre la lecture ci-dessous
Important precautions
Sulphonamide allergy
Do not take indapamide if you have a known allergy to sulphonamide medicines (such as certain antibiotics), as you may experience a similar allergic reaction.
Hypercalcaemia (High blood calcium)
Taking calcium supplements alongside indapamide significantly increases the risk of your blood calcium levels becoming dangerously high. Your doctor must monitor your blood levels regularly.
Food and drink warnings
Alcool
Drinking alcohol while taking indapamide can increase the blood-pressure-lowering effect of the medicine. This may make you feel dizzy, lightheaded, or faint, especially when standing up quickly. It is best to keep your alcohol intake within recommended limits and see how the medicine affects you before drinking.
Caffeine (Coffee, tea, energy drinks)
Caffeine can slightly reduce the amount of calcium your body absorbs and increase the amount of calcium lost in your urine. If you consume a lot of caffeine, it may make your calcium supplement less effective. Try to limit caffeine intake or space it out from when you take your supplement.
High-fibre foods (e.g., whole grains, bran) and foods high in oxalates (e.g., spinach, rhubarb)
Foods very high in fibre or oxalates can bind to calcium in the digestive tract, preventing it from being absorbed properly. If you eat these foods, try to eat them at a different time of day than when you take your calcium supplement.
Poursuivre la lecture ci-dessous
Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Clause de non-responsabilité
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions

Traitement et médicaments
Can I take Ibuprofen gel 10% and Shortec together?
Using ibuprofen gel alongside Shortec (oxycodone) is generally safe, but there is a small risk of increased side effects such as drowsiness, dizziness, or stomach irritation if the ibuprofen is absorbed into the bloodstream in significant amounts.

Traitement et médicaments
Can I take Idapamide and Ramipril together?
Taking indapamide and ramipril together can cause your blood pressure to drop too low, especially when you first start the combination. This can make you feel dizzy, lightheaded, or faint. It can also put extra strain on your kidneys.
Poursuivre la lecture ci-dessous
Historique de l'article
Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.
25 janvier 2026 | Publié à l'origine

Demandez, partagez, connectez-vous.
Parcourez les discussions, posez des questions et partagez vos expériences sur des centaines de sujets liés à la santé.

Vous ne vous sentez pas bien ?
Évaluez gratuitement vos symptômes en ligne
Inscrivez-vous à la newsletter destinée aux patients
Votre dose hebdomadaire de conseils santé clairs et fiables, rédigés pour vous aider à vous sentir informé, confiant et maître de la situation.
En vous abonnant, vous acceptez notre politique de confidentialité. Vous pouvez vous désabonner à tout moment. Nous ne vendons jamais vos données.