Can I take Folic acid and Vitamin b12 together?
Drug interaction guide
Originally published 25 Jan 2026
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Taking folic acid on its own can hide (mask) a vitamin B12 deficiency. If you have low B12 levels and take high doses of folic acid, it can fix the blood problems (like anaemia) but allow serious nerve damage to continue and get worse without being noticed.
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Why this happens
Both folic acid and vitamin B12 are needed to make red blood cells. If you are low in B12, folic acid can 'bypass' the blockage in blood cell production, making your blood tests look normal. However, folic acid cannot fix the damage to the nervous system caused by low B12, which can lead to permanent nerve damage if the B12 deficiency isn't found and treated.
What you should do
Before starting a folic acid supplement, it is important to ensure your vitamin B12 levels are normal. If you are taking folic acid, your doctor should monitor your B12 levels regularly. If you experience numbness, tingling, or weakness in your hands or feet, speak to your doctor immediately.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Clause de non-responsabilité
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historique de l'article
Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.
25 janvier 2026 | Publié à l'origine
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