Puis-je prendre Lercanidipine et Pregabalin ensemble ?

Pourquoi cela se produit

Lercanidipine works by relaxing blood vessels, which can sometimes cause fluid to leak into the tissues (swelling). Pregabalin affects the central nervous system and can also cause fluid retention and drowsiness. When used together, their similar side-effect profiles can have an additive effect on your body.

It is generally safe to take these together, but you should be aware of increased side effects. To stay safe, get up slowly from a sitting or lying position to avoid dizziness. If you notice significant swelling in your ankles, or if the drowsiness interferes with your daily activities (like driving), speak to your GP. Do not stop taking either medication without medical advice.

Troubles de la santé mentale

La prégabaline peut provoquer des pensées suicidaires ou une envie de se faire du mal. Vous devez consulter immédiatement un médecin si votre humeur change ou si vous avez des pensées de vous faire du mal.

Grossesse

Pregabalin must not be used during pregnancy unless specifically advised by a specialist, as it may increase the risk of birth defects. Effective contraception must be used during treatment.

Severe respiratory issues or opioid use

Pregabalin can cause serious, life-threatening breathing problems, especially if you already have lung disease or if you take it alongside opioid painkillers or other sedatives.

History of drug or alcohol misuse

Pregabalin carries a high risk of dependence and addiction. It is a controlled drug because it can be misused, particularly if you have a history of substance abuse.

Severe liver or kidney disease

Lercanidipine is not recommended if you have severe liver or kidney problems. Ensure your doctor is aware of your condition before starting treatment.

Alcool

It is best to avoid or strictly limit alcohol while taking these medicines. For lercanidipine, alcohol can increase the blood-pressure-lowering effect, making you feel dizzy or faint. For pregabalin, alcohol increases the risk of severe drowsiness, dizziness, and breathing problems. Combining alcohol with these medicines increases the risk of accidents and liver strain.

Pamplemousse et jus de pamplemousse

You must not eat grapefruit or drink grapefruit juice while taking lercanidipine. Grapefruit can significantly increase the amount of the medicine in your blood, making side effects like dizziness, headaches, and a fast heartbeat much more likely.

Repas riches en graisses

Lercanidipine should be taken at least 15 minutes before a meal. Taking it with or immediately after a high-fat meal can significantly increase the amount of medicine absorbed by your body, which may lead to more side effects.

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Avertissement

Ces informations sont fournies à des fins éducatives générales uniquement et ne doivent pas être considérées comme un substitut aux conseils médicaux professionnels. Consultez toujours votre médecin généraliste, votre pharmacien ou un autre professionnel de santé qualifié avant de prendre des décisions concernant vos médicaments. Les circonstances individuelles peuvent varier, et seul un professionnel de santé connaissant votre historique médical peut fournir des conseils personnalisés.