Can I take Levothyroxine and Pinefeld together?
Drug interaction guide
Originally published 25 Jan 2026
Répond aux besoins du patient lignes directrices éditoriales
- TéléchargerTélécharger
- Partager
- Langue
- Discussion
Taking levothyroxine and Pinefeld (felodipine) together is generally safe, but you should monitor for signs that your thyroid levels are changing. If your thyroid levels are not well-controlled, it can change how your body processes the blood pressure medication.
Dans cet article :
Poursuivre la lecture ci-dessous
Why this happens
Levothyroxine is a thyroid hormone, and Pinefeld (felodipine) is a calcium channel blocker used for high blood pressure. Thyroid hormones affect your metabolism. If you are hyperthyroid (too much hormone) or hypothyroid (too little), your body may break down felodipine faster or slower than usual, which could make the blood pressure medicine more or less effective.
What you should do
You can take these medicines together. However, if your doctor changes your levothyroxine dose, you should monitor your blood pressure more closely. If you feel dizzy, get a headache, or notice your heart racing, contact your doctor. Always leave a gap of at least 30 to 60 minutes between taking your levothyroxine (usually on an empty stomach) and any other medications or food.
Poursuivre la lecture ci-dessous
Important precautions
Heart disease (e.g. angina, heart failure)
Levothyroxine increases the workload on your heart. If you experience chest pain, palpitations, or shortness of breath, you must contact your doctor immediately as your dose may need adjusting.
Grapefruit consumption
Do not drink grapefruit juice or eat grapefruit while taking this medicine. It can significantly increase the amount of medicine in your blood, leading to a dangerous drop in blood pressure.
Food and drink warnings
Dairy products (Milk, Yoghurt, Cheese)
Calcium found in dairy products can significantly reduce the amount of levothyroxine your body absorbs. You should avoid eating or drinking dairy products within 4 hours of taking your dose.
Caffeine (Coffee and Tea)
Coffee and tea can interfere with how levothyroxine is absorbed. You should wait at least 30 to 60 minutes after taking your medicine before drinking coffee or tea.
Soya products
Soya can stop levothyroxine from being absorbed properly. If you eat a lot of soya, your doctor may need to monitor your thyroid levels more closely.
Papaya
Some studies suggest that eating papaya may reduce the absorption of levothyroxine. It is best to keep your intake of papaya consistent or avoid it around the time you take your medication.
Grapefruit and Grapefruit juice
Grapefruit can increase the level of this medicine in your blood, which may increase the risk of side effects like dizziness, headaches, or a rapid heartbeat. Avoid grapefruit products while taking this medicine.
Alcool
Drinking alcohol while taking Pinefeld can cause your blood pressure to drop too low, making you feel dizzy, lightheaded, or faint. It is best to limit or avoid alcohol.
Poursuivre la lecture ci-dessous
Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Clause de non-responsabilité
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions

Traitement et médicaments
Can I take Clarithromycin and Rosuvastatin together?
Taking these two medicines together can significantly increase the amount of rosuvastatin in your blood. This increases the risk of serious muscle damage (rhabdomyolysis), which can lead to kidney problems. Symptoms to watch for include unexplained muscle pain, tenderness, or weakness, especially if you also feel generally unwell or have a fever.

Traitement et médicaments
Can I take Atorvastatin and Sertraline together?
Taking atorvastatin and sertraline together may slightly increase the levels of atorvastatin in your blood. This can increase the risk of side effects, particularly muscle pain or weakness.
Poursuivre la lecture ci-dessous
Historique de l'article
Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.
25 janvier 2026 | Publié à l'origine

Demandez, partagez, connectez-vous.
Parcourez les discussions, posez des questions et partagez vos expériences sur des centaines de sujets liés à la santé.

Vous ne vous sentez pas bien ?
Évaluez gratuitement vos symptômes en ligne
Inscrivez-vous à la newsletter destinée aux patients
Votre dose hebdomadaire de conseils santé clairs et fiables, rédigés pour vous aider à vous sentir informé, confiant et maître de la situation.
En vous abonnant, vous acceptez notre politique de confidentialité. Vous pouvez vous désabonner à tout moment. Nous ne vendons jamais vos données.