Can I take Methotrexate and Side effects together?

Pourquoi cela se produit

Methotrexate works by blocking an enzyme that helps cells grow. While this treats conditions like rheumatoid arthritis or psoriasis, it also affects healthy cells in the gut, mouth, and bone marrow. It can also cause inflammation in the liver and lungs over time.

You must have regular blood tests as requested by your doctor to monitor your liver, kidneys, and blood count. Take your folic acid supplement exactly as prescribed (usually on a different day to your methotrexate) to help reduce side effects. Seek urgent medical help if you develop a high temperature, a persistent cough, yellowing of the skin, or unusual bleeding.

Pregnancy and Fathering a Child

Le méthotrexate peut provoquer de graves malformations congénitales et des fausses couches. Vous devez utiliser une contraception efficace pendant le traitement et pendant au moins 6 mois après l'arrêt. Cela concerne à la fois les hommes et les femmes.

Infection and Blood Disorders

Methotrexate can severely suppress your immune system. You must seek immediate medical attention if you develop a fever, sore throat, mouth ulcers, or unexplained bruising/bleeding, as these can be signs of life-threatening blood toxicity.

Toxicité pulmonaire et hépatique

Seek urgent medical help if you develop a persistent dry cough or shortness of breath, as this can indicate serious lung inflammation. You must also avoid alcohol, as it significantly increases the risk of permanent liver damage while on this medicine.

Alcool

You should strictly limit or avoid alcohol while taking methotrexate. Both alcohol and methotrexate can stress the liver; combining them significantly increases the risk of serious liver damage (cirrhosis or scarring). Many doctors advise no more than 1-2 units per week, or complete abstinence.

Caféine (Café, Thé, Cola)

High amounts of caffeine may reduce how well methotrexate works for some people, particularly those taking it for rheumatoid arthritis. If you notice your symptoms worsening after consuming caffeine, you may need to limit your intake.

Taking multiple medicines? Our Vérificateur d'Interactions Médicamenteuses helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Avertissement

Ces informations sont fournies à des fins éducatives générales uniquement et ne doivent pas être considérées comme un substitut aux conseils médicaux professionnels. Consultez toujours votre médecin généraliste, votre pharmacien ou un autre professionnel de santé qualifié avant de prendre des décisions concernant vos médicaments. Les circonstances individuelles peuvent varier, et seul un professionnel de santé connaissant votre historique médical peut fournir des conseils personnalisés.