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Capsules d'acitrétine pour le psoriasis

Neotigason

Acitretin will be prescribed for you by a skin specialist doctor.

Take your doses during a mealtime. Swallow the capsule(s) with a drink of milk or water.

Avoid bright sunlight or use a high-factor sun cream (SPF 15 or greater). Do not use sunbeds.

Acitretin is harmful to unborn babies. You MUST use effective contraception if you could get pregnant.

En un coup d'œil

  • Acitretin is a retinoid medicine, similar to vitamin A.

  • It treats severe psoriasis and other skin conditions by helping skin grow more normally.

  • Take capsules once daily with food, exactly as your doctor tells you.

  • Women must not become pregnant during treatment and for three years afterwards.

  • Acitretin can make your skin more sensitive to sunlight, so protect your skin.

  • Common side-effects include dry skin, lips, mouth and eyes.

About acitretin

Type de médicament

A retinoid medicine (similar to vitamin A)

Utilisé pour

Severe psoriasis and some other skin conditions

Aussi appelé

Neotigason®

Disponible sous forme de

Capsules

Acitretin is used to treat severe skin conditions where the surface of the skin has become thick and scaly. Normally, as new skin cells are produced, older ones are lost. If the skin cells in the outer layer of your skin multiply faster than normal, the old skin cells can build up on the surface of your skin, causing thick or scaly patches.

Acitretin is a retinoid medicine, which means simply that it is related to vitamin A. Our bodies use vitamin A to maintain a healthy skin. Acitretin helps to control conditions like psoriasis by making your skin grow more normally.

Acitretin is sometimes used as a treatment on its own but, more often, it is used alongside other preparations to help the skin's condition.

Before taking acitretin

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking acitretin it is important that your doctor knows:

  • If you are pregnant, trying for a baby or breastfeeding. This is because you must pas take acitretin if you think you are (or think you may be) pregnant.

  • Si vous avez des problèmes avec le fonctionnement de votre foie, ou des problèmes avec le fonctionnement de vos reins.

  • If you have high levels of fats (lipids) such as cholesterol in your blood.

  • Si vous avez le diabète (diabète sucré).

  • Si vous prenez ou utilisez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et complémentaires.

  • Si vous avez déjà eu une réaction allergique à un médicament.

How to take acitretin

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside your pack and any other information that you are given by your doctor. The leaflets will give you more information about acitretin and will provide you with a full list of the side-effects which you could experience from taking it.

  • Take the capsules exactly as your doctor tells you to. Acitretin is taken once daily. Your doctor will tell you how many capsules to take and this will also be printed on the label of the pack to remind you about what the doctor said to you. Take each of your doses with a snack, or just after eating a meal. It is a good idea to swallow the capsules with a drink of water or milk.

  • Try to take your doses of acitretin at the same time of day each day, as this will help you to remember to take them regularly. If you forget to take a dose at the usual time, take it when you remember. If you do not remember until the following day, then miss out the forgotten dose. Do not take two doses together to make up for a missed dose.

Tirer le meilleur parti de votre traitement

  • It is important for you to keep your regular appointments with your doctor. This is so your doctor can check on your progress. You will need to have regular blood tests during the treatment. The tests will check that your lipid levels are normal and that your liver remains healthy. If you are a woman, you may also need to have regular tests to confirm that you are not pregnant.

  • It can take 2-4 weeks before you start to feel the benefit from the capsules and it may take up to four months before you feel the maximum benefit. A course of treatment is likely to last for up to six months but occasionally it can be for longer than this.

  • Acitretin is harmful to unborn babies, so it is very important that you do not become pregnant while you are taking it. Your doctor will advise you about suitable contraception and this may include using more than one method. You should continue to use suitable contraception for at least three years after you finish your course of treatment. If at any time during your treatment or the three years afterwards, you think you may be pregnant, contact your doctor for advice straightaway.

  • If you buy any medicines, vitamins, or herbal preparations, please check with your doctor or a pharmacist that they are suitable for you to take with acitretin. This is because you must not take any other preparation which contains vitamin A.

  • Acitretin can cause your skin to become more sensitive to sunlight than normal. Protect your skin from sunlight even on bright but cloudy days and do not use sunbeds.

  • If you normally drink alcohol, please ask your doctor for advice. Your doctor may recommend that you do not drink alcohol while you are on this medicine.

  • If you have diabetes you may need to check your blood sugar (glucose) more frequently, as acitretin can affect the levels of sugar in your blood. Your doctor will advise you about this.

  • You must not give blood while you are on acitretin and for at least three years after you finish taking it. This is because it could cause harm to other people.

Can acitretin cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with acitretin. You will find a full list in the manufacturer's information leaflet supplied with the medicine. The unwanted effects often improve as your body adjusts to the new medicine but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common acitretin side-effects (these affect around 1 in 10 people)

Que puis-je faire si je ressens cela ?

Dry mouth, feeling thirsty, sore mouth

Try chewing sugar-free gum or sucking sugar-free sweets. If this continues, ask your doctor for advice

Dry or irritated eyes, blurred vision, and reduced night vision

Take extra care when driving at night. If this becomes troublesome, speak with your doctor

Dry skin and lips, peeling

Use a moisturising cream and lip balm regularly. After peeling, the new skin often appears more normal

Tummy (abdominal) pain, feeling sick (nausea), diarrhoea

Stick to simple meals (avoid rich or spicy foods). Drink plenty of water to replace any lost fluids

Muscle and joint pain

Let your doctor know about this so that it can be investigated

Maux de tête

Buvez beaucoup d'eau et demandez à votre pharmacien de vous recommander un antidouleur approprié. Si les maux de tête persistent, informez votre médecin

Dry or irritated nose, nosebleeds, weak nails, swollen feet and ankles, mood changes, loss of hair and changes in hair texture

Si l'un de ces éléments devient problématique, parlez-en à votre médecin

Si vous ressentez d'autres symptômes que vous pensez être dus aux capsules, veuillez consulter votre médecin ou votre pharmacien pour obtenir des conseils supplémentaires.

How to store acitretin

  • Gardez tous les médicaments hors de la portée et de la vue des enfants.

  • Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.

Informations importantes sur tous les médicaments

Informations importantes sur tous les médicaments

If you are having an operation or dental treatment, please tell the person carrying out the treatment which medicines you are taking or using.

Ne prenez jamais plus que la dose prescrite. Si vous soupçonnez que vous ou quelqu'un d'autre avez pris une surdose de ce médicament, rendez-vous au service des urgences de votre hôpital local. Emportez le contenant avec vous, même s'il est vide.

Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.

Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.

Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.

Signaler les effets secondaires d'un médicament ou d'un vaccin

Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le Site web de Yellow Card.

vérificateur de symptômes

Vous n'êtes pas sûr de mélanger des médicaments ?

Vérifiez les interactions possibles entre les médicaments, les compléments et les aliments avant de les prendre ensemble.

Questions fréquemment posées

Can I take acitretin if I have diabetes?

If you have diabetes, your doctor needs to be aware of this before you start taking acitretin. You may need to monitor your blood sugar (glucose) levels more frequently, as this medication can affect them. Your doctor will provide specific advice on managing this.

How long will I need to be on acitretin treatment?

A typical course of treatment with acitretin is likely to last for up to six months. However, in some cases, your doctor may decide to extend the treatment for a longer period.

What should I do if my skin becomes very dry due to acitretin?

Dry skin and lips are common side-effects of acitretin. To manage this, you should regularly use a moisturising cream and lip balm. It's often observed that after an initial period of peeling, new skin appears more normal.

Why do I need regular blood tests while taking acitretin?

Regular blood tests are essential to monitor your progress and ensure your safety while on acitretin. These tests help your doctor check that your lipid levels (fats like cholesterol) remain normal and that your liver is functioning healthily. If you are a woman, regular tests may also be needed to confirm you are not pregnant.

Can I use sunbeds while taking acitretin?

No, you must not use sunbeds while taking acitretin. This medication can make your skin much more sensitive to sunlight, so it's important to protect your skin from the sun, even on bright but cloudy days.

What kind of drinks should I take with acitretin capsules?

It is a good idea to swallow acitretin capsules with a drink of water or milk. This should be done with a snack or just after eating a meal.

Lectures complémentaires et références

À propos de l'auteurVoir la biographie complète

Image de l'auteur

Michael Stewart, MRPharmS

Responsable de l'examen des notices de médicaments – Contractuel, Pharmacien

BPharm (Hons), MRPharmS

Michael est un pharmacien communautaire exerçant dans les Midlands et le South Yorkshire avec plus de 20 ans d'expérience dans le conseil sur les médicaments et les conditions médicales. Il possède une solide expérience en formation dans le domaine de la santé, ayant produit et dispensé des cours de formation pour les équipes de pharmacie et le personnel des établissements de soins résidentiels, y compris les infirmières. Il a également contribué aux comités consultatifs de pharmacie pour la gestion des affections de faible gravité dans la communauté.

À propos du critique

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Sid Dajani

Sultan Dajani a obtenu son diplôme à la London School of Pharmacy en 1994 et est devenu le plus jeune membre élu du conseil de la Royal Pharmaceutical Society depuis sa fondation en 1842.

Historique de l'article

Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.

  • Next review due: 25 Sept 2027
  • 20 Sept 2024 | Dernière version

    Dernière mise à jour par

    Michael Stewart, MRPharmS

    Revu par

    Sid Dajani
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