Toxine botulique de type A pour la migraine
Botox
Revu par Sid DajaniDernière mise à jour par Michael Stewart, MRPharmSDernière mise à jour 19 sept. 2023
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Botulinum toxin type A is a specialist treatment for migraine.
To be eligible for this treatment you must have headaches for 15 or more days each month, with migraine headaches being on at least eight of these days.
It will be given by multiple injections into the muscles around your head and neck.
If you experience any difficulty swallowing, speaking, or breathing after the treatment, speak with your doctor immediately.
En un coup d'œil
Botulinum toxin type A is a neurotoxin used to prevent chronic migraine headaches.
It is given by injection into muscles around the head and neck.
To be eligible, you must have frequent headaches and have tried other migraine prevention medicines.
Injections are typically repeated every 12 weeks if the treatment is successful.
Common side-effects include pain at injection sites and muscle pain or weakness.
Seek immediate medical help if you experience difficulty swallowing, speaking, or breathing.
About botulinum toxin type A
Type de médicament | A bacterial neurotoxin |
Utilisé pour | To prevent headaches associated with chronic migraine in adults |
Aussi appelé | Onabotulinumtoxin A (in US); Alluzience®; Azzalure®; Bocouture®; Botox®; Nuceiva®; Xeomin® |
Disponible sous forme de | Injection |
Botulinum toxin type A is a protein substance which is produced by the bacterium Clostridium botulinum. It is a neurotoxin which means that it interferes with the way nerves work. To be eligible for this treatment you must have headaches for 15 or more days each month, with migraine headaches being on at least eight of these days. You must also have tried several other medicines to prevent migraine before this treatment is prescribed for you.
Botulinum toxin type A is thought to work in chronic migraine by relaxing muscles and by blocking the pain signals which are involved in the development of a migraine. These actions may have the effect of stopping a migraine headache from being triggered.
Botulinum toxin injections are also used for other reasons (including cosmetic purposes, muscle spasms, bladder problems, and excessive sweating). This leaflet does not cover the use of botulinum toxin type A in these ways.
Before being treated with botulinum toxin type A
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before being treated with botulinum toxin type A for migraine, make sure that your doctor knows:
Si vous êtes enceinte, essayez d'avoir un bébé ou allaitez.
If you have an infection or any swelling near any of the areas that will be injected.
If you have any muscle problems, particularly any muscle weakness.
If you have ever had any difficulty in swallowing or with your breathing.
Si vous prenez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et les médecines complémentaires.
Si vous avez déjà eu une réaction allergique à un médicament.
How you will be given botulinum toxin type A
Before you start the treatment, ask to read the manufacturer's printed information leaflet from inside the pack. It will give you more information about Botox® and will provide you with a full list of the side-effects which you may experience from having it.
You will be given botulinum toxin type A by a doctor who is trained in the use of this treatment. It will be injected into the muscles around your head and neck in several different places.
If the treatment proves successful for you, your doctor is likely to recommend that it is repeated every 12 weeks.
Tirer le meilleur parti de votre traitement
If you are having an operation or dental treatment, tell the person carrying out the treatment that you have received botulinum toxin type A.
Can botulinum toxin type A cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with botulinum toxin type A. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects may occur following a treatment session even if you have been free from side-effects on previous treatments. You should speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common Botox® side-effects (these affect fewer than 1 in 10 people) | Que puis-je faire si je ressens cela ? |
Pain at the sites where you have been injected, neck and muscle pain or stiffness, muscle weakness, skin rash and itching | These should soon pass, but if any becomes troublesome, speak with your doctor |
Worsening of headache or migraine | Parlez-en avec votre médecin |
Eyelid drooping or swelling, paralysis of the face | Parlez-en avec votre médecin |
Important: if you experience any difficulty swallowing, speaking, or breathing, speak with your doctor immediately or go to your local accident and emergency department straightaway.
If you experience any other symptoms which you think may be due to the treatment, speak with your doctor or pharmacist for further advice.
Informations importantes sur tous les médicaments
Informations importantes sur tous les médicaments
Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.
If you buy any medicines, check with a pharmacist that they are safe to use alongside this treatment.
Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.
Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.
Signaler les effets secondaires d'un médicament ou d'un vaccin
Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le Site web de Yellow Card.

Vous n'êtes pas sûr de mélanger des médicaments ?
Vérifiez les interactions possibles entre les médicaments, les compléments et les aliments avant de les prendre ensemble.
Questions fréquemment posées
What is botulinum toxin type A and how does it relate to Botox®?
Botulinum toxin type A is a protein substance derived from a bacterium which primarily interferes with nerve function. Botox® is one of several brand names, alongside others like Alluzience®, Azzalure®, Bocouture®, and Xeomin®, under which botulinum toxin type A is available for medical treatments, including chronic migraine.
Are there specific criteria I need to meet to be eligible for botulinum toxin type A treatment for migraine?
Yes, to be eligible for this treatment for migraine, you must experience headaches for 15 or more days each month, with migraine headaches occurring on at least eight of those days. Additionally, you need to have attempted and found insufficient several other migraine prevention medicines before this treatment will be considered.
How often will I need to receive botulinum toxin type A injections if they are effective for my migraines?
If the treatment is successful in managing your chronic migraines, your doctor will likely recommend that the injections are repeated approximately every 12 weeks.
Are there any specific situations where I should inform other healthcare professionals about my botulinum toxin type A treatment?
Yes, if you are planning to have an operation or dental treatment, it is important to inform the person carrying out the procedure that you have received botulinum toxin type A injections.
What should I do if I experience rare but serious side effects like difficulty swallowing or breathing after treatment?
If you experience any serious side effects such as difficulty swallowing, speaking, or breathing, you should seek immediate medical attention. Contact your doctor straightaway or go directly to your local accident and emergency department.
Lectures complémentaires et références
- Manufacturer's PIL, Botox® 50, 100 and 200 Allergan Units; AbbVie Ltd, The electronic Medicines Compendium. Dated April 2023.
- Médicaments Complets BNF 89e Édition; Association Médicale Britannique et Société Royale Pharmaceutique de Grande-Bretagne, Londres.
À propos de l'auteurVoir la biographie complète

Michael Stewart, MRPharmS
Responsable de l'examen des notices de médicaments – Contractuel, Pharmacien
BPharm (Hons), MRPharmS
Michael est un pharmacien communautaire exerçant dans les Midlands et le South Yorkshire avec plus de 20 ans d'expérience dans le conseil sur les médicaments et les conditions médicales. Il possède une solide expérience en formation dans le domaine de la santé, ayant produit et dispensé des cours de formation pour les équipes de pharmacie et le personnel des établissements de soins résidentiels, y compris les infirmières. Il a également contribué aux comités consultatifs de pharmacie pour la gestion des affections de faible gravité dans la communauté.
À propos du critique

Sid Dajani
Sultan Dajani a obtenu son diplôme à la London School of Pharmacy en 1994 et est devenu le plus jeune membre élu du conseil de la Royal Pharmaceutical Society depuis sa fondation en 1842.
Historique de l'article
Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.
Article également disponible en Anglais, Allemand, Espagnol, Français, Italien, Portugais, Hindi, Hébreu, Arabe, and Suédois.
Prochaine révision prévue : 18 sept. 2026
19 sept. 2023 | Dernière version

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