Pommade de calcitriol pour le psoriasis
Silkis
Revu par Sid DajaniDernière mise à jour par Michael Stewart, MRPharmSDernière mise à jour 19 nov. 2024
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Apply a thin layer of ointment twice a day, morning and evening.
Do not use more than the maximum recommended amount of ointment each day.
Remember to wash your hands well after using calcitriol. This will help to prevent accidentally getting it on other areas of your skin, which could cause irritation.
Calcitriol can cause skin irritation. If this becomes severe, stop using the ointment and ask your doctor or pharmacist for further advice.
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About calcitriol
Type de médicament | A topical vitamin D analogue |
Utilisé pour | Plaque psoriasis in adults and in children aged over 12 years |
Aussi appelé | Silkis® |
Disponible sous forme de | Ointment |
Calcitriol is used to treat psoriasis en plaques - this is the most common type of psoriasis. It is a condition where red scaly patches called plaques develop on your skin. The most common areas affected are over your elbows and knees, the scalp, and the lower part of your back. The patches may vary in size from time to time and can be itchy. Treatment for psoriasis aims to clear the plaques as much as possible.
Psoriasis is caused by cells in the outer layer of your skin multiplying faster than normal. This causes the older and dead skin cells to build up on the surface of your skin, causing the red scaly patches. Calcitriol works by slowing this overproduction of skin cells which eases the inflamed, scaly areas. It is similar to vitamin D, which is a vitamin essential for healthy skin.
Calcitriol can be taken orally as capsules to treat certain bone problems. Information on this use can be found in our separate medicine leaflet Calcitriol capsules.
Before using calcitriol
Retour au sommaireTo make sure that this is the right treatment for you, before you start using calcitriol ointment it is important that your doctor knows:
Si vous êtes enceinte, essayez d'avoir un bébé ou allaitez.
If you have been told you have a form of psoriasis known as erythrodermic or pustular psoriasis. This is because more severe forms of psoriasis like these should only be treated with the close supervision from a skin specialist doctor.
If you have been told you have high calcium levels in your blood, or if your body has problems processing calcium.
If you have any problems with the way your kidneys work, or any problems with the way your liver works.
If you are taking any other medicines or using any other skin preparations. This includes any medicines which are available to buy without a prescription, as well as herbal and complementary medicines.
Si vous avez déjà eu une réaction allergique à un médicament.
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How to use calcitriol
Retour au sommaireBefore you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about applying calcitriol and will provide you with a full list of the side-effects which you could experience from using it.
Wash and dry the areas of your skin which are affected and then apply a thin layer of ointment. Do this twice each day - it is usually recommended that you apply calcitriol in the morning, and in the evening before going to bed.
You should not use more than 30 g of calcitriol ointment per day, and you should not apply it to more than a third of your body surface area each day. As a guide, a third of your body is approximately one full arm and one full leg. This is because calcitriol is absorbed through your skin and can cause problems if more than these amounts are used.
Wash your hands well afterwards. This will help to prevent the ointment from getting on to any areas of your skin which are unaffected by psoriasis, and causing irritation.
Tirer le meilleur parti de votre traitement
Retour au sommaireEssayez de respecter vos rendez-vous réguliers avec votre médecin. Cela permet à votre médecin de suivre vos progrès.
If you are also using a moisturiser for your skin, use this first and then wait until it has soaked into your skin before you apply calcitriol ointment.
Do not cover any areas of skin that have been treated with calcitriol with a dressing or a bandage. This is because it would cause you to absorb too much calcium into your bloodstream and this will cause problems.
If you have been advised to use calcitriol on your face, apply it carefully so that you do not get any ointment into your eyes. Also, remember to apply a thin layer only, as there is a greater chance it could cause irritation on your face.
You should start to see an improvement in your skin within a few weeks. This improvement will continue for a further few weeks until you feel the full benefit. Continue to apply the ointment regularly for as long as you have been recommended so that you get the full benefit.
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Can calcitriol cause problems?
Retour au sommaireAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with calcitriol. You will find a full list in the manufacturer's information leaflet supplied with the medicine. The unwanted effects often improve as your body adjusts to the new medicine but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common calcitriol side-effects (these affect fewer than 1 in 10 people) | What can I do if I experience this? |
Skin redness, itching, discomfort or irritation | This is usually mild, but if it continues or becomes severe, please speak with your doctor as it may be a sign of an allergic reaction |
Important: there is a risk of fire when creams and ointments are absorbed by fabrics (such as clothing or bedsheets), making them flammable. A spark or flame can easily ignite the fabric. The risk is highest when large amounts of paraffin-based products are applied and absorb into fabrics. However, there is also a risk when non-paraffin products are used. Be aware of this fire hazard when repeatedly using large amounts of any skin product. Do not smoke or go near naked flames.
When used as directed by your doctor or pharmacist, this product will be applied in small quantities on small areas of skin. There should be minimal absorption into fabrics and a lower risk of fire.
If you experience any other symptoms which you think may be due to the ointment, please speak with your doctor or pharmacist for further advice.
How to store calcitriol
Retour au sommaireGardez tous les médicaments hors de la portée et de la vue des enfants.
Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.
Calcitriol ointment only keeps for eight weeks once the tube has been opened, so do not use any ointment from a tube which has been opened for longer than this. Request a fresh supply through your doctor.
Informations importantes sur tous les médicaments
Retour au sommaireInformations importantes sur tous les médicaments
Si vous achetez des médicaments, vérifiez avec un pharmacien qu'ils sont sûrs à prendre avec vos autres médicaments.
If you are having an operation or dental treatment, please tell the person carrying out the treatment which medicines you are taking or using.
Cette préparation est à utiliser uniquement sur la peau. Si quelqu'un en avale accidentellement, rendez-vous au service des urgences de votre hôpital local. Emportez le contenant avec vous, même s'il est vide.
Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.
Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.
Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.
Signaler les effets secondaires d'un médicament ou d'un vaccin
Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le site web Yellow Card.

Vous n'êtes pas sûr de mélanger des médicaments ?
Vérifiez les interactions possibles entre les médicaments, les compléments et les aliments avant de les prendre ensemble.
Lectures complémentaires et références
- Manufacturer's PIL, Silkis® 3 micrograms per gram ointment; Galderma (U.K) Ltd, The electronic Medicines Compendium. Dated May 2024.
- Médicaments Complets BNF 89e Édition; Association Médicale Britannique et Société Royale Pharmaceutique de Grande-Bretagne, Londres.
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Historique de l'article
Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.
Next review due: 25 Nov 2027
19 nov. 2024 | Dernière version

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