Lévothyroxine
Eltroxin, Vencamil, Levoxyl
Revu par Sid DajaniDernière mise à jour par Michael Stewart, MRPharmSDernière mise à jour 18 mars 2023
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Levothyroxine is a replacement or supplement thyroid hormone.
You will need regular blood tests to check your thyroid levels, particularly at the beginning of your treatment.
If you experience any side-effects, speak with your doctor as your dose may need adjusting.
En un coup d'œil
Levothyroxine is a medicine used to treat an underactive thyroid gland (hypothyroidism).
It works by replacing the thyroid hormone your body isn't making enough of.
Take it once a day, usually before breakfast, at least 30 minutes before your first meal.
Vous aurez besoin de prises de sang régulières pour vérifier vos niveaux de thyroïde.
Do not take indigestion remedies, calcium, or iron supplements at the same time as levothyroxine.
If you notice side-effects like heart palpitations or chest pain, tell your doctor straight away.
Treatment with levothyroxine is usually lifelong.
About levothyroxine
Type de médicament | Thyroid hormone |
Utilisé pour | Glande thyroïde sous-active (hypothyroïdie) |
Aussi appelé (Royaume-Uni) | Eltroxin®; Vencamil®; |
Aussi appelé (États-Unis) | Ermeza®; Euthyrox®; Levoxyl®; Levo-T®; Synthroid®; Thyquidity®; Tirosint®; Unithroid® |
Disponible sous forme de | Comprimés et médicaments liquides oraux |
If you have an underactive thyroid gland, it means that your thyroid gland does not produce enough thyroid hormone. This is a condition known as hypothyroidism. Levothyroxine (which is also called levothyroxine sodium) restores the balance of thyroid hormone in your body. It is very similar to thyroxine, the hormone which your body produces naturally.
Before taking levothyroxine
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking levothyroxine it is important that your doctor knows:
If you are pregnant or breastfeeding. This is so your doctor can keep a check on your baby.
If you have a heart problem such as heart failure or angina, or if you have high blood pressure (hypertension).
If you have ever been told your adrenal gland is unable to produce enough of the hormone cortisol, a condition called adrenal insufficiency.
If you have been told your thyroid is overactive (producing too much thyroxine).
If you have high levels of sugar (glucose) in your blood (diabetes mellitus)
If you have been told you have a problem regulating the levels of water in your body, a rare condition known as diabetes insipidus.
Si vous avez de l'épilepsie.
Si vous prenez ou utilisez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et complémentaires.
Si vous avez déjà eu une réaction allergique à un médicament.
How to take levothyroxine
Before you start this treatment, read the manufacturer's printed information leaflet from inside your pack. The manufacturer's leaflet will give you more information about levothyroxine and a full list of the side-effects which you may experience from taking it.
Take levothyroxine exactly as your doctor tells you to. Your doctor will ask you to take one dose each day, preferably before your breakfast. The number of tablets you need to take for each dose will be adjusted to suit you.
There are multiple strengths of tablet (12.5 micrograms, 25 micrograms, 50 micrograms, 75 micrograms and 100 micrograms) and your dose may be a combination of different-strength tablets.
As a guide, it is usual for adults to start by taking a daily dose of 50-100 micrograms, and for this to be increased gradually to a daily dose of 100-200 micrograms. Your doctor or pharmacist will tell you what dose is right for you.
If levothyroxine has been prescribed for a child, the doctor will tell you what dose to give. The dose for children depends upon their weight, age and what they are being treated for.
Take levothyroxine at least half an hour before eating the first meal of the day.
Most people find that levothyroxine tablets are easily swallowed. If you do have swallowing difficulties, some brands of tablet can be added to a little water and allowed to disperse before swallowing. Ask your pharmacist to check if your brand of tablet will disperse in water. Alternatively, ask your doctor to prescribe the oral liquid medicine for you.
If you forget to take a dose, take it as soon as you remember, if it is still within two or three hours of your usual time. If it is longer than this before you remember, skip the forgotten dose. Do not take two doses together to make up for a missed dose.
Tirer le meilleur parti de votre traitement
Try to keep your regular appointments with your doctor so your progress can be monitored. You will need regular blood tests to check your thyroid levels, particularly in the early stages of your treatment.
If you buy any medicines, check with a pharmacist that they are safe to take with levothyroxine. Levothyroxine should not be taken at the same time as indigestion remedies or preparations containing calcium or iron (which are contained in some vitamin products). These types of medicines reduce the amount of levothyroxine absorbed by your body. Leave at least two hours between taking your dose of levothyroxine and any such preparation.
Calcium or iron found in the food you eat can also reduce the amount of levothyroxine absorbed by your body. Try to take your dose at least 30 minutes before your first meal of the day.
If you have diabetes you may need to check your blood glucose more frequently, as levothyroxine may affect the levels of sugar in your blood. Your doctor will be able to advise you about this.
If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking levothyroxine.
Treatment with levothyroxine is usually lifelong. Continue to take this medicine unless your doctor tells you to stop.
Can levothyroxine cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the ones associated with levothyroxine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. Experiencing side-effects may be an indication that your dose needs adjusting, so speak with your doctor if you experience any of the symptoms listed below.
L evothyroxine side-effects | Que puis-je faire si je ressens cela ? |
Se sentir malade (nausée) ou être malade (vomissements) | Optez pour des aliments simples - évitez les repas riches ou épicés |
Diarrhée | Buvez beaucoup d'eau pour remplacer les fluides perdus |
Maux de tête | Buvez beaucoup d'eau et demandez à votre pharmacien de vous recommander un analgésique approprié. Si les maux de tête persistent, consultez votre médecin |
A feeling that your heart is pounding (palpitations) or chest pain | Informez votre médecin de cela dès que possible |
Feeling restless, feeling flushed, feeling hot, sweating, difficulty sleeping, loss of weight, muscle cramps, temporary loss of hair, itchy rash, menstrual changes | Discuss these with your doctor |
Si vous ressentez d'autres symptômes que vous pensez être dus à ce médicament, parlez-en à votre médecin ou à votre pharmacien.
How to store levothyroxine
Gardez tous les médicaments hors de la portée et de la vue des enfants.
Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.
Informations importantes sur tous les médicaments
Informations importantes sur tous les médicaments
Ne prenez jamais plus que la dose prescrite. Si vous soupçonnez que vous ou quelqu'un d'autre avez pris une surdose de ce médicament, rendez-vous au service des urgences de votre hôpital local. Emportez le contenant avec vous, même s'il est vide.
Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.
Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.
Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.
Signaler les effets secondaires d'un médicament ou d'un vaccin
Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le Site web de Yellow Card.

Vous n'êtes pas sûr de mélanger des médicaments ?
Vérifiez les interactions possibles entre les médicaments, les compléments et les aliments avant de les prendre ensemble.
Questions fréquemment posées
What should I do if I forget to take a dose of levothyroxine?
If you miss a dose, take it as soon as you remember, but only if it's within two or three hours of your usual dose time. If it's been longer than that, skip the forgotten dose and just take your next dose at the regular time. Do not take two doses at once to make up for a missed dose.
Are there any foods or other medicines I should avoid when taking levothyroxine?
Yes, you should avoid taking indigestion remedies or products containing calcium or iron at the same time as levothyroxine. These can reduce how much levothyroxine your body absorbs. Leave at least two hours between taking levothyroxine and these types of medicines or supplements. Similarly, calcium or iron in food can also affect absorption, so try to take levothyroxine at least 30 minutes before your first meal of the day.
Will I need to take levothyroxine forever?
Treatment with levothyroxine is usually lifelong. You should continue to take this medicine unless your doctor specifically tells you to stop.
What should I do if I experience side-effects from levothyroxine?
Experiencing side-effects might mean your dose needs to be adjusted. You should speak with your doctor if you experience any side-effects, especially palpitations, chest pain, restlessness, feeling flushed, sweating, difficulty sleeping, weight loss, muscle cramps, temporary hair loss, an itchy rash, or changes to your menstrual cycle. If you experience any other symptoms you think might be related to the medicine, discuss them with your doctor or pharmacist.
How should I store my levothyroxine medicine?
Keep all levothyroxine out of the reach and sight of children. Store it in a cool, dry place, away from direct heat and light.
Lectures complémentaires et références
- Manufacturer's PIL, Eltroxin® 50 and 100 micrograms Tablets; ADVANZ Pharma (formerly Concordia International), The electronic Medicines Compendium. Dated May 2022.
À propos de l'auteurVoir la biographie complète

Michael Stewart, MRPharmS
Responsable de l'examen des notices de médicaments – Contractuel, Pharmacien
BPharm (Hons), MRPharmS
Michael est un pharmacien communautaire exerçant dans les Midlands et le South Yorkshire avec plus de 20 ans d'expérience dans le conseil sur les médicaments et les conditions médicales. Il possède une solide expérience en formation dans le domaine de la santé, ayant produit et dispensé des cours de formation pour les équipes de pharmacie et le personnel des établissements de soins résidentiels, y compris les infirmières. Il a également contribué aux comités consultatifs de pharmacie pour la gestion des affections de faible gravité dans la communauté.
À propos du critique

Sid Dajani
Sultan Dajani a obtenu son diplôme à la London School of Pharmacy en 1994 et est devenu le plus jeune membre élu du conseil de la Royal Pharmaceutical Society depuis sa fondation en 1842.
Historique de l'article
Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.
Article également disponible en Anglais, Allemand, Espagnol, Français, Italien, Portugais, Hindi, Hébreu, Arabe, and Suédois.
Next review due: 17 Sept 2027
18 mars 2023 | Dernière version

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