Montélukast pour l'asthme
Singulair
Revu par Sid DajaniDernière mise à jour par Michael Stewart, MRPharmSDernière mise à jour 3 Sept 2024
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Take montelukast regularly every evening.
Your doctor will prescribe a reliever inhaler for you to use in case you have an asthma attack. Make sure that you keep it with you all the time.
The most common side-effects of montelukast are respiratory infections, tummy (abdominal) pain and headache.
In some cases taking montelukast has led to changes in mood and behaviour in children, teenagers and adults. If you notice any worrying signs or changes in behaviour in yourself or a child taking montelukast discuss it with your doctor as soon as possible.
En un coup d'œil
Montelukast is a medicine used to treat asthma, taken once a day in the evening.
It works by blocking substances in the body that cause inflammation in the lungs.
Montelukast will not give immediate relief during an asthma attack.
Tell your doctor if you are pregnant, trying for a baby, or breastfeeding.
Common side-effects include tummy pain, feeling sick, headache, and infections.
Seek medical advice for worsening asthma symptoms or mood and behaviour changes.
About montelukast
Type de médicament | A leukotriene receptor antagonist |
Utilisé pour | Asthme |
Aussi appelé | Singulair® |
Disponible sous forme de | Tablets, chewable tablets (for children), and sachets of granules (for children) |
Asthme is a common condition caused by inflammation in the smaller airways of the lungs. The inflammation irritates the muscles around the airways and causes them to constrict. This causes your airways to narrow. It is then more difficult for air to get in and out of your lungs. This causes the typical symptoms of wheeze, chest tightness and shortness of breath. The inflammation also causes the lining of your airways to make extra mucus which causes coughing.
Asthma symptoms can flare up from time to time and there may be no apparent reason why. However, some people find that symptoms are made worse by triggers such as exercise and pollen. These things cause your body to produce chemical substances called leukotrienes, which cause the inflammation. Montelukast helps control the symptoms of asthma by blocking the effects of these leukotrienes. It is especially helpful for people whose asthma symptoms are brought on by exercise or seasonal allergies such as hay fever.
Before taking montelukast
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking montelukast it is important that your doctor knows:
Si vous êtes enceinte, essayez d'avoir un bébé ou allaitez.
Si vous prenez ou utilisez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et complémentaires.
Si vous avez déjà eu une réaction allergique à un médicament.
How to take montelukast
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about montelukast and will provide you with a full list of the side-effects which you could experience from taking it.
Take montelukast once every day, in the evening. The dose for adults is one 10 mg tablet. If montelukast has been prescribed for your child, the dose will depend on their age: it is 4 mg for children aged from 6 months to 5 years, and 5 mg for children aged from 6 years to 14 years.
The 10 mg (adult) tablet can be swallowed with a drink of water and can be taken either before or after food.
If your child has been prescribed tablets to take, they are cherry-flavoured chewable tablets. The tablets should preferably be taken 'on an empty stomach', which means your child should take them about an hour before a meal, or wait until two hours afterwards. They should be chewed before being swallowed.
If your child has been prescribed granules (in sachets), these can simply be poured into the mouth and swallowed. Alternatively if your child prefers, you can mix the granules into a small amount of cold, soft food (such as yoghurt, ice cream or mashed fruit or vegetables). It doesn't matter if montelukast granules are taken before or after meals but they should not be mixed into drinks or hot food.
Remember to take montelukast regularly every day, even if your asthma is well controlled. Try not to miss any of your doses but if you do forget, just take your next dose when it is due. Do not take two doses together to make up for a forgotten dose.
Tirer le meilleur parti de votre traitement
Try to keep your regular appointments with your doctor. This is so your doctor can check on your (or your child's) progress.
Montelukast will not give you immediate relief if you are having an asthma attack. Your doctor will prescribe a reliever inhaler for you to use if this happens. Make sure that you keep it with you all the time in case you need to use it.
If you find that your asthma symptoms are getting worse, or that you need to use the reliever inhaler more regularly than usual, please contact your doctor or nurse for advice straightaway.
Do not smoke. Smoking causes severe irritation and damage to the lungs. It will make your condition worse and will reduce the beneficial effects of your medication.
If you buy any medicines, check with a pharmacist that they are suitable for you to take. Some anti-inflammatory painkillers and aspirin can make asthma symptoms worse in some people.
Can montelukast cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains the most common ones associated with montelukast. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common montelukast side-effects (these affect fewer than 1 in 10 people) | Que puis-je faire si je ressens cela ? |
Tummy (abdominal) pain, feeling sick (nausea), diarrhoea | Speak with your doctor if this continues |
Maux de tête | Buvez beaucoup d'eau et demandez à votre pharmacien de vous recommander un antidouleur approprié. Si les maux de tête persistent, informez votre médecin |
Throat and chest infections, high temperature (fever), skin rash | Si cela pose problème, parlez-en à votre médecin |
Important : if you get any of the following symptoms, please let your doctor know straightaway. These can be a sign of a very rare but serious disorder called Churg-Strauss syndrome: flu-like symptoms, tingling feelings or numbness in your arms or legs, difficulties with breathing, and skin rash.
Important : In some cases taking montelukast has led to changes in mood and behaviour in children, teenagers and adults. These changes have included anxiety, irritability, restlessness, agitation, aggressive behaviour and depression. In very rare cases hallucinations, obsessive-compulsive behaviours and suicidal thinking and behaviour have occurred. If you notice any worrying signs or changes in behaviour in yourself, or a child, taking montelukast, discuss it with your doctor as soon as possible.
Si vous ressentez d'autres symptômes que vous pensez être dus au médicament, veuillez consulter votre médecin ou votre pharmacien pour obtenir des conseils supplémentaires.
How to store montelukast
Gardez tous les médicaments hors de la portée et de la vue des enfants.
Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.
Informations importantes sur tous les médicaments
Informations importantes sur tous les médicaments
Never take more than the prescribed dose. If you suspect that you or someone else might have had an overdose of this medicine, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.
Si vous subissez une opération ou un traitement dentaire, informez la personne qui effectue le traitement des médicaments que vous prenez.
Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.
Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.
Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.
Signaler les effets secondaires d'un médicament ou d'un vaccin
Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le Site web de Yellow Card.

Vous n'êtes pas sûr de mélanger des médicaments ?
Vérifiez les interactions possibles entre les médicaments, les compléments et les aliments avant de les prendre ensemble.
Questions fréquemment posées
Can montelukast cause cough?
The article mentions that inflammation in the airways causes extra mucus, leading to coughing in asthma. However, it does not state that montelukast itself causes a cough as a side effect. Common side effects listed for montelukast include tummy pain, nausea, diarrhoea, headache, and throat/chest infections, but not cough directly.
Can montelukast make asthma worse?
Montelukast helps control asthma symptoms by blocking the effects of leukotrienes, which cause inflammation. The article advises contacting a doctor if asthma symptoms worsen or if a reliever inhaler is needed more regularly, as this indicates a need for medical advice, not necessarily that montelukast made it worse.
Does montelukast cause drowsiness?
The article does not list drowsiness as a common or rare side effect of montelukast. The reported side effects mainly include gastrointestinal issues, headaches, and infections. More serious but rare side effects involve mood and behavioural changes, but not drowsiness.
How quickly does montelukast provide relief for asthma symptoms?
Montelukast will not give you immediate relief if you are experiencing an asthma attack. For immediate relief during an asthma attack, your doctor will prescribe a reliever inhaler that you should keep with you.
What should I do if I forget to take my montelukast dose?
If you forget to take a dose, you should just take your next dose when it is due. Do not take two doses together to make up for a forgotten dose.
Is it safe to get dental treatment or an operation while taking montelukast?
Yes, but it is important to inform the person carrying out the dental treatment or operation about all the medicines you are taking, including montelukast.
Are there any specific foods or drinks I should avoid while taking montelukast?
For adult tablets, montelukast can be taken before or after food. For children's chewable tablets, they are preferably taken 'on an empty stomach', meaning about an hour before a meal or two hours after. For granules, they can be mixed with cold, soft food but should not be mixed into drinks or hot food. The article does not mention avoiding any specific food types.
Lectures complémentaires et références
- Manufacturer's PIL, Singulair® 10 mg tablets; Organon Pharma (UK) Limited, The electronic Medicines Compendium. December 2022.
- Manufacturer's PIL, Singulair® Paediatric 4 mg tablets; Organon Pharma (UK) Limited, The electronic Medicines Compendium. Dated September 2022.
- Manufacturer's PIL, Singulair® Paediatric 4 mg granules; Merck Sharp & Dohme Limited, The electronic Medicines Compendium. Dated September 2022.
- Médicaments Complets BNF 89e Édition; Association Médicale Britannique et Société Royale Pharmaceutique de Grande-Bretagne, Londres.
À propos de l'auteurVoir la biographie complète

Michael Stewart, MRPharmS
Responsable de l'examen des notices de médicaments – Contractuel, Pharmacien
BPharm (Hons), MRPharmS
Michael est un pharmacien communautaire exerçant dans les Midlands et le South Yorkshire avec plus de 20 ans d'expérience dans le conseil sur les médicaments et les conditions médicales. Il possède une solide expérience en formation dans le domaine de la santé, ayant produit et dispensé des cours de formation pour les équipes de pharmacie et le personnel des établissements de soins résidentiels, y compris les infirmières. Il a également contribué aux comités consultatifs de pharmacie pour la gestion des affections de faible gravité dans la communauté.
À propos du critique

Sid Dajani
Sultan Dajani a obtenu son diplôme à la London School of Pharmacy en 1994 et est devenu le plus jeune membre élu du conseil de la Royal Pharmaceutical Society depuis sa fondation en 1842.
Historique de l'article
Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.
Article également disponible en Anglais, Allemand, Espagnol, Français, Italien, Portugais, Hindi, Hébreu, Arabe, and Suédois.
Prochaine révision prévue : 3 sept. 2027
3 Sept 2024 | Dernière version

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